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Ku80/XRCC5 Antibody (S10B1)

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Product Details

Summary
Product Discontinued
View other related Ku80/XRCC5 Primary Antibodies

Order Details


    • Catalog Number
      NB500-703
    • Availability
      Product Discontinued

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Ku80/XRCC5 Antibody (S10B1) Summary

Immunogen
Human placental extract.
Localization
Nuclear
Specificity
This reacts with a 80 kDa protein known as Ku (p80).
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
XRCC5
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Control
Human Tonsil Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publication using NB500-703.

Reactivity Notes

Cross-reacts with Human and Monkey.Does not cross-react with Rabbit, Mouse or Cow.Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for Ku80/XRCC5 Antibody (S10B1)

  • 80kDa
  • ATP-dependent DNA helicase 2 subunit 2
  • ATP-dependent DNA helicase II 80 kDa subunit
  • CTC85
  • CTCBF
  • EC 3.6.4.-
  • FLJ39089
  • G22P2
  • KARP1
  • KARP-1
  • Ku80
  • Ku86 autoantigen related protein 1,86 kDa subunit of Ku antigen
  • Ku86
  • Ku86DNA repair protein XRCC5
  • KUB2
  • NFIV
  • Thyroid-lupus autoantigen
  • TLAA
  • X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining)CTC box-binding factor 85 kDa subunit
  • X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining; Ku autoantigen, 80kD)
  • X-ray repair cross-complementing protein 5
  • X-ray repair, complementing defective, repair in Chinese hamster
  • XRCC5

Background

Originally identified as an autoantigen, the Ku proteins are nuclear proteins found in eukaryotes. They exist as a heterodimer consisting of Ku 70 and Ku 80, and migrate at approximately 70 and 80 kDa, respectively. They bind to DNA ends at double strand breaks. The Ku proteins interact with the DNA dependent protein kinase (DNA PK), and participate in the targeting of DNA PK to DNA. The Ku proteins may participate in numerous cellular processes, including DNA repair and replication, cell signaling, and proliferation, transcriptional activation, and apoptosis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Ku80/XRCC5
Antibody (S10B1)
NB500-703
Ku80/XRCC5 Antibody (S10B1)
Species: Hu, Pm, Bv(-), Mu(-), Rb(-)
Applications: IHC

Publications for Ku80/XRCC5 Antibody (NB500-703)(1)

We have publications tested in 1 confirmed species: Human.


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Control Lysate(s)

Human Tonsil Whole Tissue Lysate (Adult Whole Normal)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol XRCC5
Entrez