Ku80/XRCC5 Products

Antibodies
Ku80/XRCC5 Antibody
Ku80/XRCC5 Antibody
NBP1-56408
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Ku80/XRCC5 Antibody
Ku80/XRCC5 Antibody
NB100-508
Species: Hu, Mu, Rt, Ha
Applications: WB, IP
Host: Rabbit Polyclonal
Ku80/XRCC5 Antibody (3D8)
Ku80/XRCC5 Antibody (3D8)
H00007520-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
Ku80/XRCC5 Overexpression Lys ...
Ku80/XRCC5 Overexpression Lysate (...
NBL1-17918
Applications: WB
Proteins
Ku80/XRCC5 Recombinant Protei ...
Ku80/XRCC5 Recombinant Protein
H00007520-P01
Species: Hu
Applications: WB, ELISA, PA
Ku80/XRCC5 Recombinant Protei ...
Ku80/XRCC5 Recombinant Protein Ant...
NBP1-87829PEP
Species: Hu
Applications: AC
Ku80/XRCC5 Peptide
Ku80/XRCC5 Peptide
NB100-508PEP
Applications: AC
RNAi
Ku80/XRCC5 RNAi
Ku80/XRCC5 RNAi
H00007520-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Ku80, also known as XRCC5, plays a role in many diverse processes including cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis.

As one half of the heterodimer complex Ku, Ku80 is required for proper maintenance of the telomeric C strand. Ku80 also plays a role in DNA repair as an essential subunit of DNA-dependent protein kinase (DNA-PK) that phosphorylates certain transcription factors (Sp1, Oct-1 and p53). The heterodimer Ku binds double stranded DNA breaks for non-homologous end joining repair. Ku mutants are defective in T-DNA integration and over-expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 7520
Alternate Names
  • ATP-dependent DNA helicase II 80 kDa subunit
  • Ku80
  • ATP-dependent DNA helicase 2 subunit 2
  • G22P2
  • TLAA
  • EC 3.6.4.-
  • CTCBF
  • X-ray repair, complementing defective, repair in Chinese hamster
  • CTC85
  • X-ray repair cross-complementing protein 5
  • Ku86 autoantigen related protein 1,86 kDa subunit of Ku antigen
  • Thyroid-lupus autoantigen
  • 80kDa
  • X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining; Ku autoantigen, 80kD)
  • NFIV
  • KUB2
  • KARP1
  • KU80
  • FLJ39089
  • KARP-1
  • Ku86DNA repair protein XRCC5
  • X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining)CTC box-binding factor 85 kDa subunit

Research Areas for Ku80/XRCC5

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Non-homologous end-joining
Phospho-Specific
Stem Cell Markers

Bioinformatics Tool for Ku80/XRCC5

Discover related pathways, diseases and genes to Ku80/XRCC5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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