KLHL6 Antibody

Western Blot: KLHL6 Antibody [NBP1-46128] - Staining of Human (A), Mouse (B) and Rat (C) Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

KLHL6 Antibody Summary

• Description: Novus Biologicals Goat KLHL6 Antibody (NBP1-46128) is a polyclonal antibody validated for use in WB and ELISA. Anti-KLHL6 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-SERTKPRMHEFQSE corresponding to internal region according to NP_569713.2.
• Epitope: internal region
• Predicted Species: Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: KLHL6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 80 kDa band observed in human tonsil and NIH3T3 lysates (calculated MW of 70.4 kDa band according to human NP_569713.2 and of 70.2 kDa band according to mouse NP_899246.2).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KLHL6 Antibody

• FLJ00029
• kelch-like 6 (Drosophila)
• kelch-like protein 6
• kelch-like protein KLHL6
• KLHL6

Background

KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KLHL6 Antibody (NBP1-46128)(2)

Publications using NBP1-46128

• Choi J, Lee K et al. Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2. Nat Cell Biol 2018-01-05 [PMID: 29695787] (WB, Human)
• Gupta-Rossi N, Storck S, Griebel PJ et al. Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells. Mol Immunol 2003-03-01 [PMID: 12617994]

Bioinformatics

• Gene Symbol: KLHL6
• Entrez:
  • 89857(Human)
  • 239743(Mouse)
  • 287974(Rat)
• Uniprot:
  • NP_569713.2(Human)