KLHL12/C3IP1 Antibody

Images

 
Western Blot: KLHL12/C3IP1 Antibody [NB120-14233] - E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, XpSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

KLHL12/C3IP1 Antibody Summary

Immunogen
Synthetic peptide: KHAKKEREES LPNLLQYVRM PLLTPRYITD VIDAEPFIRC SLQCRDLVDE AKKFHLRPEL RSQMQGPRTR ARLGANEVLL VVGGFGSQQS PIDVVEKYDP KTQEWSFLPS ITRKRRYVAS VSLHDRIYVI GGYDGRSRLS SVECLDYTAD EDGVWYSVAP MNVRRGLAGA TTLGDMIYVS GGFDGSRRHT SMERYDPNID, corresponding to amino acids 205-404 of Human C3IP1.
Specificity
C3IP1
Predicted Species
Xenopus (92%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Chicken
Gene
KLHL12
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunocytochemistry/Immunofluorescence
Application Notes
WB: Predicted molecular weight: 68 kDa. Optimal dilutions/concentrations should be determined by the end user.Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 28428367).
Control
KLHL12/C3IP1 Overexpression Lysate
Publications
Read Publication using
NB120-14233 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KLHL12/C3IP1 Antibody

  • C3IP1kelch-like protein 12
  • CUL3-interacting protein 1
  • DKIR
  • FLJ27152
  • kelch-like 12 (Drosophila)
  • kelch-like protein C3IP1

Background

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least KLHL12/C3IP1. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Xp
Applications: WB, ICC/IF

Publications for KLHL12/C3IP1 Antibody (NB120-14233)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for KLHL12/C3IP1 Antibody (NB120-14233) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics

Gene Symbol KLHL12
Entrez
Uniprot