Western Blot: KLHL12/C3IP1 Antibody [NB120-14233] - E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( ...read more
WB: Predicted molecular weight: 68 kDa. Optimal dilutions/concentrations should be determined by the end user.Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 28428367).
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for KLHL12/C3IP1 Antibody
C3IP1kelch-like protein 12
CUL3-interacting protein 1
kelch-like 12 (Drosophila)
kelch-like protein C3IP1
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least KLHL12/C3IP1. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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