KiSS1R/GPR54 Antibody

Images

 
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1929] - Human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1929] - Analysis of anti-KISS1R / GPR54 antibody with human brain, glioblastoma.
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1929] - Human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: KiSS1R/GPR54 Antibody [NLS1929] - Human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications Flow, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

KiSS1R/GPR54 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human KISS1R / GPR54.
Localization
Cell Membrane
Specificity
Human KISS1R / GPR54. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%), Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KISS1R
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 - 1:1000
  • Immunohistochemistry-Paraffin 8 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Mouse (83%), Rat (83%), Bat (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KiSS1R/GPR54 Antibody

  • AXOR12
  • AXOR12hypogonadotropin-1
  • G protein-coupled receptor 54
  • GPR54
  • GPR54kiSS-1R
  • G-protein coupled receptor 54
  • G-protein coupled receptor OT7T175
  • HOT7T175
  • Hypogonadotropin-1
  • KISS1 receptor
  • kiSS-1 receptor
  • KiSS1R
  • KiSS-1R
  • Kisspeptins receptor
  • Metastin Receptor
  • OT7T175

Background

GPR54 is a Metastin Receptor. Metastin, also known as KiSS-1, is a metastasis suppressor gene. Mutations in GPR54 have been shown to cause autosomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, suggesting that GPR54 is a key regulator for the onset of puberty (Seminara et al. 2003). GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KISS1R
Entrez