Kir3.3 Products

Description

The Kir3.3 (KCNJ9) encodes for a 393 amino acid long, 44 kDA, G-protein activated inward rectifier potassium channel protein that creates heteromultimeric pore-forming complexes. The Kir3.3 gene has been investigated in generalized epilepsy, meniere's disease, pertussis, lung cancer, schizophrenia, and diabetes mellitus. It interacts with the DRD4, KCNJ6, ADRB2, KCNJ3, and DRD2 genes in potassium transporting pathways (inward and outward), G-Beta gamma signaling, neurotransmitter receptor binding and downward transmission in the postsynaptic cell, and ion currents in synaptic transmission.

Bioinformatics

Entrez	116560 Rat 16524 Mouse 3765 Human 50599 Rat
Uniprot	Q92806 Human
Product By Gene ID	3765
Alternate Names	G protein-activated inward rectifier potassium channel 3 G protein-coupled inward rectifier potassium channel GIRK-3 GIRK3KIR3.3 Inward rectifier K(+) channel Kir3.3 inwardly rectifier K+ channel KIR3.3 Kir3.3 Potassium channel, inwardly rectifying subfamily J member 9 potassium inwardly-rectifying channel, subfamily J, member 9

Diseases related to Kir3.3

Discover more about diseases related to Kir3.3.

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Dysequilibrium Syndrome
Nervousness
Pain
Epilepsy
Hyperalgesia
Sclerosis
Neurodegenerative Disorders
Idiopathic Generalized Epilepsy
Epilepsy, Generalized
Metabolic Diseases
Substance Withdrawal Syndrome
Globus Hystericus

Pathways for Kir3.3

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Localization
Neurogenesis
Transport
Cell Proliferation
Mrna Transcription
Gliogenesis
Brain Development
Synaptic Transmission

PTMs for Kir3.3

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Glycosylation

Bioinformatics Tool for Kir3.3

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