KIR2DS1/CD158h Antibody (1127B) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1127B
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 750

Order Details

KIR2DS1/CD158h Antibody (1127B) [Alexa Fluor® 750] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
HEK293 human embryonic kidney cell line transfected with human KIR2DS1/CD158h
Met1-His245
Accession # Q14954
Specificity
Detects human KIR2DS1/CD158h in flow cytometry. Clone 1127B recognizes KIR2DS1 and some alleles of KIR2DL1, both members of the killer cell immunoglobulin-like receptor (KIR) family. Because Clone 1127B displays partial cross-reactivity with KIR2DL1, co-staining with Mouse Anti-Human KIR2DL1 Clone 143211 (Catalog # FAB1844F) is recommended.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DS1/CD158h Antibody (1127B) [Alexa Fluor® 750]

  • killer cell immunoglobulin-like receptor 2DS1
  • CD158a
  • CD158h
  • EB6ActI
  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
  • KIR2DS1
  • p50.1

Background

The KIRs comprise a family of 14 polymorphic and homologous activating and inhibitory receptors expressed primarily on CD56dim NK cells. KIR2DS1 is an activating receptor with high homology to the inhibitory receptor KIR2DL1. Both KIR2DL1 and KIR2DS1 bind to HLA-C alleles containing the C2 epitope. KIR2DS1 and KIR2DL1 expression regulates NK cell licensing and activation in a number of immune contexts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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