Kinesin 5C Antibody

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Western Blot: Kinesin 5C Antibody [NB120-5630] - Analysis of kinesin 5C on human retinal extract.

Product Details

Summary
Reactivity Hu, Bv(-), Mu(-)Species Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Kinesin 5C Antibody Summary

Immunogen
Synthetic Peptide: C A(938) V H A I R G G G G S S S N S T H Y Q K(957)
Localization
Cytoplasmic
Specificity
This is specific for kinesin 5C and does not detect other kinesin isotypes.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KIF5C
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.5 ug/ml
Application Notes
WB: Detects an approx. 110 kDa (predicted molecular weight: 110 kDa), an unidentified band is also detected at 100 kDa.

Reactivity Notes

Expected cross-reactivity with Rat (90%) base on sequence homology.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS containing 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Kinesin 5C Antibody

  • heavy chain, neuron-specific
  • KIF 5C
  • kinesin family member 5C
  • Kinesin heavy chain neuron-specific 2
  • MGC111478
  • NKHC
  • NKHC2NKHC-2

Background

Kinesins are a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KIF5C
Entrez