KIF14 Antibody

Western Blot: KIF14 Antibody [NB110-40678] - Detection of Human KIF14 on HeLa whole cell lysate using NB110-40678. KIF14 was also immunoprecipitated by other rabbit anti-KIF14 antibodies.

Immunohistochemistry: KIF14 Antibody [NB110-40678] - Sample: FFPE section of human breast carcinoma (left) and formaldelyde-fixed HeLa cells (right). Antibody: Affinity purified rabbit anti-KIF14 used at a dilution of 1:200 (1ug/ml) and 1:100 (2ug/ml). Detection: DAB (left) and red-fluorescent goat anti-rab

• Reactivity: Hu
• Applications: WB, IHC, IP, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

KIF14 Antibody Summary

• Description: Novus Biologicals Rabbit KIF14 Antibody (NB110-40678) is a polyclonal antibody validated for use in IHC, WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1600 and the C-terminus (residue 1648) of human Kinesin Family Member 14 using the numbering given in entry NP_055690.1 (GeneID 9928).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KIF14
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KIF14 Antibody

• KIAA0042MGC142302
• kinesin family member 14
• kinesin-like protein KIF14

Background

The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of the transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 14 (KIF14) is an overexpressed potential oncogene in the 1q region of genomic gain in breast cancer cell lines associated with poor prognosis breast cancer. The gain of chromosome 1q likely reflects oncogene amplification. As such KIF14 may be a potential therapeutic target and indicator of oncogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KIF14
• Entrez:
  • 9928(Human)
• Uniprot:
  • NP_055690.1(Human)