KCC3/SLC12A6 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: KCC3/SLC12A6 Antibody [NBP3-03772] - Analysis of U2OS cells using KCC3/SLC12A6 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

• Reactivity: Hu
• Applications: ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

KCC3/SLC12A6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KCC3/SLC12A6 Antibody - BSA Free (NBP3-03772) is a polyclonal antibody validated for use in ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human KCC3/SLC12A6 (NP_598408.1). MSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC12A6
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
• Theoretical MW: 128 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for KCC3/SLC12A6 Antibody - BSA Free

• ACCPN
• agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome)
• DKFZp434D2135
• EC 1.2.4.1
• EC 6.1.1.3
• Electroneutral potassium-chloride cotransporter 3
• KCC3
• KCC3A
• KCC3B
• KCC3potassium chloride cotransporter 3
• K-Cl cotransporter 3
• potassium chloride cotransporter KCC3a-S3
• potassium-chloride transporter-3a
• potassium-chloride transporter-3b
• SLC12A6
• solute carrier family 12 (potassium/chloride transporters), member 6
• solute carrier family 12 member 6

Background

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC12A6