katanin-p80 Antibody

Western Blot: katanin-p80 Antibody [NB100-75489] - E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-KAT )

Product Discontinued

katanin-p80 Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 1a.a. to 220a.a. from Katanin p80(a 655a.a. long protein)
• Localization: Predominantly cytoplasmic. Also localized to the interphase centrosome and mitotic spindle poles.
• Specificity: katanin-p80
• Clonality: Polyclonal
• Host: Chicken
• Gene: KATNB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
• Control:

  katanin-p80 Overexpression Lysate

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for katanin-p80 Antibody

• KAT
• katanin (80 kDa)
• katanin p80 (WD repeat containing) subunit B 1
• katanin p80 (WD40-containing) subunit B 1
• Katanin p80 subunit B1
• katanin p80 WD40-containing subunit B1
• p80 katanin

Background

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, whereas the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KATNB1
• Entrez:
  • 10300(Human)
  • 74187(Mouse)
  • 291852(Rat)
• Uniprot:
  • Q59G59(Human)