KANK2 Antibody - BSA Free

Immunohistochemistry-Paraffin: KANK2 Antibody [NBP1-89080] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

• Reactivity: Hu, Rt, Mu
• Applications: WB, ICC/IF, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

KANK2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KANK2 Antibody - BSA Free (NBP1-89080) is a polyclonal antibody validated for use in IHC, WB, ICC/IF and IP. Anti-KANK2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: SQHIPTAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVQ
• Predicted Species: Mouse (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KANK2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Immunoprecipitation
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: IP, WB, ICC/IF reported in scientific literature (PMID: 25961457). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  KANK2 Protein (NBP1-89080PEP)

Reactivity Notes

Rat, Human reactivity reported in scientific literature (PMID: 25961457). Use in Rat reported in scientific literature (PMID:25961457).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for KANK2 Antibody - BSA Free

• ANKRD25
• ankyrin repeat domain 25
• Ankyrin repeat domain-containing protein 25
• DKFZp434N161
• FLJ20004
• KIAA1518SRC1-interacting protein
• kidney ankyrin repeat-containing protein 2
• KN motif and ankyrin repeat domain-containing protein 2
• KN motif and ankyrin repeat domains 2
• Matrix-remodeling-associated protein 3
• matrix-remodelling associated 3
• MGC119707
• MXRA3
• SIP
• SRC-1 interacting protein
• SRC-1-interacting protein

Background

KANK2/SIP was first identified during a genome wide-screen for proteins that interact with the SRC transcriptional coactivator. KANK2/SIP was also identified by domain and phylogenetic analysis to be a member of the KANK ankyrin-repeat domain-containing protein family. KANK related proteins possess a conserved ankyrin-repeat and coiled-coil domain. KANK2, as well as other KANK proteins, appear to play a role in the formation of actin stress fibers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KANK2 Antibody (NBP1-89080)(1)

Publication using NBP1-89080

• Gee HY, Zhang F, Ashraf S et al. KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. J Clin Invest 2015-06-01 [PMID: 25961457] (WB, ICC/IF, IP, Human, Rat)

Bioinformatics

• Gene Symbol: KANK2