Kallikrein 1 Antibody

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications IP, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Kallikrein 1 Antibody Summary

Immunogen
Peptide with sequence C-FNTWIRETMAEND corresponding to C-Terminus according to Uniprot Mouse NP_034769.4.
Epitope
FNTWIRETMAEND - C Terminus
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KLK1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 1:10 - 1:500
  • Peptide ELISA Detection limit 1:4000
Application Notes
WB: Preliminary experiments gave an approx. 55 kDa band in mouse liver, heart and testis lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 28.8 kDa band according to NP_034769.4. The 55 kDa band was successfully blocked by incubation with the immunizing peptide.
Publications
Read Publication using NBP1-49884.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Kallikrein 1 Antibody

  • EC 3.4.21
  • EC 3.4.21.35
  • glandular kallikrein 1
  • hK1
  • Kallikrein 1
  • kallikrein 1, renal/pancreas/salivary
  • kallikrein serine protease 1
  • kallikrein-1
  • Kidney/pancreas/salivary gland kallikrein
  • KLK1
  • Klk6
  • KLKR
  • Tissue kallikrein

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Kallikrein 1 Antibody (NBP1-49884)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLK1
Entrez
Uniprot