JMJD6/PSR Antibody

Western Blot: JMJD6/PSR Antibody [NBP2-98745] - Lane A: NIH3T3 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:46 kDaObserved band size:50 kDa

Immunocytochemistry/Immunofluorescence: JMJD6/PSR Antibody [NBP2-98745] - Immunofluorescence staining of JMJD6/PSR in HeLa cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-human JMJD6/PSR polyclonal antibody (1:5000) at 4C overnight. Then cells were stained with the Alexa Fluor(R)594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to nucleus..

Product Discontinued

JMJD6/PSR Antibody Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human JMJD6/PSR.
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: JMJD6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:1500-1:50000
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for JMJD6/PSR Antibody

• bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
• EC 1.14.11
• EC 1.14.11.-
• Histone arginine demethylase JMJD6
• JmjC domain-containing protein 6
• JMJD6
• jumonji domain containing 6
• Jumonji domain-containing protein 6
• KIAA0585PSR
• Lysyl-hydroxylase JMJD6
• Peptide-lysine 5-dioxygenase JMJD6
• Phosphatidylserine receptorPTDSR
• Protein PTDSR
• PSR
• PTDSR
• PTDSR1

Background

JMJD6 encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: JMJD6