Jarid1D Antibody

Product Discontinued

Jarid1D Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1490 and 1540 of human SMC (mouse) homolog, Y chromosome (jumonji, AT rich interactive domain 1D ) using the numbering given in entry NP_004644.2 (GeneID 8284).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KDM5D
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-10 ug/mg lysate
  • Western Blot 1:2000-1:10000
• Theoretical MW: 174 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Jarid1D Antibody

• EC 1.14.11
• EC 1.14.11.-
• Histocompatibility Y antigen
• Histone demethylase JARID1D
• HY
• H-Y
• HYASmcy homolog, Y-linked (mouse)
• JARID1DAT rich interactive domain 1D (RBP2-like)
• Jumonji/ARID domain-containing protein 1D
• KDM5D
• KIAA0234jumonji, AT rich interactive domain 1D
• lysine (K)-specific demethylase 5D
• Protein SmcY
• selected mouse cDNA on Y, human homolog of
• SMC homolog, Y chromosome
• Smcy homolog, Y chromosome
• Smcy homolog, Y-linked

Background

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Jarid1D Antibody (NB100-93292)(1)

Publication using NB100-93292

• Komura K, Jeong SH, Hinohara K et al. Resistance to docetaxel in prostate cancer is associated with androgen receptor activation and loss of KDM5D expression. Proc. Natl. Acad. Sci. U.S.A. 2016-05-31 [PMID: 27185910]

Bioinformatics

• Gene Symbol: KDM5D
• Entrez:
  • 8284(Human)
• Uniprot:
  • Q9BY66(Human)