Jak1 Antibody


Western Blot: Jak1 Antibody [NBP1-31815] - JAK1 antibody detects JAK1 protein analysis A. 30 ug GL261 whole cell lysate/extract B. 30 ug C8D30 whole cell lysate/extract C. 30 ug NIH-3T3 whole cell lysate/extract ...read more
Immunocytochemistry/ Immunofluorescence: JAK1 Antibody [NBP1-31815] - Analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.
Western Blot: JAK1 Antibody [NBP1-31815] - Sample (30 ug of whole cell lysate) A: Hep G2 5% SDS PAGE; antibody diluted at 1:1000.

Product Details

Reactivity Hu, Mu, Rt, Po, Bv, Ca, Ch, RMSpecies Glossary
Applications WB, ICC/IF

Order Details

Jak1 Antibody Summary

Recombinant protein encompassing a sequence within the C-terminus region of human JAK1. The exact sequence is proprietary.
Predicted Species
Rat (98%), Porcine (100%), Bovine (99%), Rhesus Macaque (100%), Chicken (93%), Canine (99%). Backed by our 100% Guarantee.
Protein A purified
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  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
Theoretical MW
133 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (85%).

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
0.01% Thimerosal
Protein A purified

Alternate Names for Jak1 Antibody

  • EC 2.7.10
  • Jak1
  • JAK-1
  • JAK1Atyrosine-protein kinase JAK1
  • JAK1B
  • Janus kinase 1EC
  • JTK3


JAK1 (Janus kinase 1) a 130 kD non-receptor protein tyrosine kinase family and a member of the JAK subfamily is a widely expressed, membrane associated kinase involved in signal transduction pathways from interferon alpha, beta, and gamma receptors, all class II receptors, cytokine receptors that utilize the common gamma chain subunit for signaling, and cytokine receptors that utilize the gp130 subunit for signaling. JAK1 phosphorylates Stat proteins and SHP2. This kinase is constitutively expressed, but expression can be increased with interferon- alpha and interferon- gamma stimulation through transcription. JAK1 activity is increased by cytokine receptor-ligand binding and can be decreased by SOCS proteins, SHP2 protein phosphatase, and PPAR agonists. JAK1 is modified by phosphorylation and has been shown to associate with IFN- alpha receptor beta chain, IFN- gamma receptor alpha chain, IL-10 receptor alpha chain, IL-2 receptor beta chain, and IL-4 receptor alpha chain. The Poly6044 antibody recognizes the N-terminal region of human JAK1 and has been shown to be useful for Western blotting.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

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Blogs on Jak1.

Using a STAT3 antibody in chromatin immunoprecipitation (ChIP)
Signal transducer and activator of transcription 3 (STAT3) is an important oncogenic transcriptional factor that mediates tumor induced immune suppression.  Specifically, STAT3 transmits signals from cytokines and growth factor receptors in the pla...  Read full blog post.

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Gene Symbol JAK1