ITPR2 Antibody

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP3-12318] - Mouse heart. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40Xmangification.

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP3-12318] - Mouse heart. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 20X mangification.

Immunohistochemistry-Paraffin: ITPR2 Antibody [NBP3-12318] - Mouse heart. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40Xmangification.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ITPR2 Antibody Summary

• Description: Novus Biologicals Rabbit ITPR2 Antibody (NBP3-12318) is a polyclonal antibody validated for use in IHC, WB, ELISA and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide taken within amino acid region 100-150 on rat Inosital 1,4,5-triphosphate receptor type 2 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITPR2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Immunoprecipitation 1:200
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ITPR2 Antibody

• inositol 14,5-triphosphate receptor, type 2
• inositol 14,5-trisphosphate receptor type 2
• InsP3R2
• IP3 receptor isoform 2
• IP3 receptor
• IP3R 2
• IP3R2
• ITPR2
• Type 2 inositol 14,5-trisphosphate receptor
• Type 2 InsP3 receptor

Background

Inositol 1,4,5-triphosphate (IP3) receptors are a form of ligand-gated ion channels that are activated by cytosolic Ca2+ and IP3. They are localized to intracellular membranes, such as the endoplasmic reticulum, and mediate the mobilization of intracellular Ca2+ stores. IP3 receptors play an important role in intracellular Ca2+ signaling in a variety of cell types. There are three IP3 receptor subtypes; IP3R1, IP3R2 and IP3R3, which exist as homo- and heterotetramers. All subtypes are closely associated with calmodulin and FK506-binding protein and are modulated through phosphorylation by PKA, PKC, PKG and CaMKII.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITPR2