Recombinant Human Isopeptidase T/USP5 Protein

Product Discontinued

Recombinant Human Isopeptidase T/USP5 Protein Summary

• Description: Recombinant protein for Human Isopeptidase T/USP5
  
  

  Source:E. coli
  Amino Acid Sequence:(P45974)

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: USP5
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 97 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM Tris, 10 Mmn B-mercaptoethanol, pH 7.5.
• Concentration: 0.4 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human Isopeptidase T/USP5 Protein

• Deubiquitinating enzyme 5
• EC 3.1.2.15
• EC 3.4.19.12
• Isopeptidase T
• IsoT
• ISOTubiquitin carboxyl-terminal hydrolase 5
• ubiquitin isopeptidase T
• ubiquitin specific peptidase 5 (isopeptidase T)
• ubiquitin specific protease 5 (isopeptidase T)
• ubiquitin thioesterase 5
• Ubiquitin thiolesterase 5
• ubiquitin-specific protease-5 (ubiquitin isopeptidase T)
• Ubiquitin-specific-processing protease 5
• USP5

Background

Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: USP5