Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 5 (USP5) is a member of this family. The upregulation of USP5 has been found to be associated with fetal Down syndrome. Alternate names for USP include ubiquitin carboxyl-terminal hydrolase 5, ubiquitin thioesterase 5, ubiquitin-specific-processing protease 5, deubuiquitinating enzyme 5, isopeptidase T, and ISOT.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
8078 |
| Alternate Names |
- Deubiquitinating enzyme 5
- EC 3.1.2.15
- EC 3.4.19.12
- Isopeptidase T
- IsoT
- ISOTubiquitin carboxyl-terminal hydrolase 5
- ubiquitin isopeptidase T
- ubiquitin specific peptidase 5 (isopeptidase T)
- ubiquitin specific protease 5 (isopeptidase T)
- ubiquitin thioesterase 5
- Ubiquitin thiolesterase 5
- ubiquitin-specific protease-5 (ubiquitin isopeptidase T)
- Ubiquitin-specific-processing protease 5
|
