IP3R3 Antibody - BSA Free

Immunohistochemistry-Paraffin: IP3R3 Antibody [NBP1-21399] - Section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-IP3R3 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Immunoprecipitation: IP3R3 Antibody [NBP1-21399] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-IP3R3 antibody used for IP at 3 mcg/mg lysate. IP3R3 was also immunoprecipitated by rabbit anti-IP3R3 antibody NBP1-21400 which recognizes a downstream e

• Reactivity: Hu
• Applications: IHC, IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

IP3R3 Antibody - BSA Free Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 625 and 675 of human inositol 1,4,5-triphosphate receptor, type 3 using the numbering given in entry NP_002215.2 (GeneID 3710).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITPR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:500 - 1:2000
  • Immunoprecipitation 2 - 10 ug/mg lysate
• Application Notes: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for IP3R3 Antibody - BSA Free

• FLJ36205
• inositol 14,5-triphosphate receptor, type 3
• inositol 14,5-trisphosphate receptor type 3
• InsP3R3
• IP3 receptor isoform 3
• IP3 receptor
• IP3R 3
• IP3R
• IP3R3
• ITPR3
• Type 3 inositol 14,5-trisphosphate receptor
• Type 3 InsP3 receptor

Background

IP3R3 (inositol 1,4,5-triphosphate receptor type 3) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian IP3R receptors: IP3R1, IP3R2, and IP3R3. IP3R3 has been shown to play a role in olfactory mucus secretion and in the taste perception of sweet, savory (umami), and bitter substances.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IP3R3 Antibody (NBP1-21399)(1)

Publication using NBP1-21399

• Lee HJ, Jung YH, Choi GE et al. Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis Cell Death Differ. 2020-07-23 [PMID: 32704090] (Human)

Bioinformatics

• Gene Symbol: ITPR3
• Entrez:
  • 3710(Human)
• Uniprot:
  • NP_002215.2(Human)