Integrin alpha 9 Antibody (560201) [DyLight 405]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 560201
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Integrin alpha 9 Antibody (560201) [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant human Integrin alpha 9
  Val89-Leu169
  Accession # Q13797
• Specificity: Detects human Integrin alpha 9 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Integrin alpha 1, 2, 2b, 3, 4, 5, 6, 6 (x1), 8, 10, 11, D, E, L, M, V, X, recombinant mouse Integrin alpha 7 (x2) or 9 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ITGA9
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Integrin alpha 9 Antibody (560201) [DyLight 405]

• ALPHA-RLC
• Integrin alpha 9
• integrin alpha-9
• Integrin alpha-RLC
• integrin, alpha 9
• ITGA4L
• ITGA9
• RLC
• RLC-alpha

Background

Integrin alpha-9 is a protein that functions as a receptor for VCAM1, osteopontin and cytotactin, is located in the airway epithelium, smooth muscle, hepatocytes, and skeletal muscle and is encoded by a gene comprised of 1035 amino acids and weighs approximately 114 kDa. Studies are being conducted on several diseases and disorders related to this protein, including lung cancer, Lynch syndrome, hypertension, PANDAS, medulloblastoma, carcinoma, nasopharyngitis, colorectal cancer, breast cancer, arthritis, and melanoma. Integrin alpha-9 has also been shown to have interactions with FIGF, ITGB7, SAT1, SPP1, and ITGB1 in pathways such as the CDK5, Tec kinases signaling, integrin-mediated cell adhesion, signal transduction, and hypertrophic cardiomyopathy pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGA9