IL6R Antibody (AP-MAB0848)


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Product Details

Reactivity MuSpecies Glossary
Applications B/N, Flow, IP
1.0 mg/ml

Order Details

IL6R Antibody (AP-MAB0848) Summary

Mouse recombinant IL-6R alpha chain
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
A 0.2 um filtered solution in PBS - Azide free
No Preservative
1.0 mg/ml
Protein A or G purified


  • Blocking/Neutralizing 50-200 molar excess
  • Flow Cytometry 1:10-1:1000
  • Immunoprecipitation 1:10-1:500
Application Notes
Extremely low level of LPS (< 0.002EU/ug IgG)

Alternate Names for IL6R Antibody (AP-MAB0848)

  • CD126 antigen
  • CD126
  • gp80
  • IL-6 receptor subunit alpha
  • IL-6R 1
  • IL-6R subunit alpha
  • IL-6R-1
  • IL6RA
  • IL-6RA
  • IL-6R-alpha
  • interleukin 6 receptor alpha subunit
  • interleukin 6 receptor
  • interleukin-6 receptor subunit alpha
  • Membrane glycoprotein 80
  • MGC104991


CD126 is an 80 kD IL-6 receptor alpha chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. High affinity IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor beta chain (CD130 or gp130). CD126 binds IL-6 with low affinity, but does not signal. The beta chain (gp130, CD130) does not bind IL-6 by itself, but associates with the alpha-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor stimulation and differentiation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for IL6R Antibody (NBP1-06670). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for an antibody to detect murine IL6 receptor and would like to use it to block the receptor in vivo in mouse. Your data sheet briefly states, that this antibody can be used for "Blocking/Neutralizing 50-200 molar excess" - but not more infor
    • The blocking assay was performed using murine IL-6Ra over-expressing mouse fibroblasts. NBP1-06670 blocks IL-6 induced cell proliferation in a dose dependent manner, however no in vivo testing has been performed in house.

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol IL6R

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