IL6R Products

Description

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Bioinformatics

Entrez	16194 Mouse 3570 Human
Uniprot	NP_000556 Human NP_000556.1 Human NP_852004 Human P08887 Human P22272 Mouse
Product By Gene ID	3570
Alternate Names	CD126 antigen CD126 gp80 IL-6 receptor subunit alpha IL-6R 1 IL-6R subunit alpha IL-6R-1 IL6RA IL-6RA IL-6R-alpha interleukin 6 receptor alpha subunit interleukin 6 receptor interleukin-6 receptor subunit alpha Membrane glycoprotein 80 MGC104991

Research Areas for IL6R

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytokine Research
Immunology
Innate Immunity