IL-3 Antibody (4E6)

Product Discontinued

IL-3 Antibody (4E6) Summary

• Immunogen: Recombinant full length protein (Human).
• Localization: Secreted
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 1:100-1:2000
• Application Notes: ELISA Suitable for sandwich ELISA of IL3 in the following combination: capture - NB120-10084, NB120-10080, NB120-10083, conjugate NB120-10082. Optimal dilutions and concentrations should be determined by the end user.

Reactivity Notes

Cross-reacts with Human.Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for IL-3 Antibody (4E6)

• Hematopoietic growth factor
• IL3
• IL-3
• IL-3MGC79398
• interleukin 3 (colony-stimulating factor, multiple)
• interleukin-3
• Mast cell growth factor
• mast-cell growth factor
• MCGF
• MCGFMGC79399
• MULTI-CSF
• multilineage-colony-stimulating factor
• Multipotential colony-stimulating factor
• P-cell stimulating factor
• P-cell-stimulating factor

Background

The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for IL-3 Antibody (NB110-8392). (Showing 1 - 1 of 1 FAQ).

1. I am looking to purchase NB110-8392, but need a formulation without Sodium Azide. Would a product like this be available?
   • I have searched our product database for an IL3 antibody without sodium azide but was not successful. My recommendation would be to go ahead and purchase the antibody you were originally looking at, NB110-8392, and using our AbSelect Antibody Purification Kit, cat#860-0005 to clean it up. This kit is designed for removing substances such as azide, BSA, glycine and tris.

Bioinformatics

• Gene Symbol: IL3
• Entrez:
  • 3562(Human)
• Uniprot:
  • P08700()