IL-27 Antibody (B-G49)

• Reactivity: Hu
• Applications: ELISA(Det)
• Clone: B-G49
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.1 mg/ml

IL-27 Antibody (B-G49) Summary

• Description: Novus Biologicals Mouse IL-27 Antibody (B-G49) (NBP3-18128) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant IL-27. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells
• Specificity: Recognizes both natural and recombinant IL-27
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IL27
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA Detection (Matched Antibody Pair) 0.05-0.5ug/ml
• Application Notes: The suggested coating concentration range below should be optimised by each laboratory for each application. This ELISA detection antibody paired with the ELISA capture antibody (NBP3-18127) is used for highly specific and sensitive detection of IL-27.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS. With 1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: Affinity purified

Alternate Names for IL-27 Antibody (B-G49)

• IL-27 p28 subunit
• IL-27 subunit alpha
• IL27
• IL-27
• IL27A
• IL-27-A
• IL27-A
• IL27p28
• IL30
• interleukin 27
• interleukin 30
• interleukin-27 subunit alpha
• MGC71873
• p28IL-27A

Background

IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL27