IL-10R alpha Antibody (AP-MAB0852) - Azide and BSA Free

Product Discontinued

IL-10R alpha Antibody (AP-MAB0852) - Azide and BSA Free Summary

• Immunogen: Mouse recombinant soluble IL-10R
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: IL10RA
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • CyTOF-ready
  • Flow Cytometry 1:10-1:1000
• Application Notes: Flow Cytometry as well as in vitro and in vivo blocking of ligand binding. Extremely low level of LPS (< 0.002EU/ug IgG). This antibody is CyTOF ready.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for IL-10R alpha Antibody (AP-MAB0852) - Azide and BSA Free

• CD210 antigen
• CDw210a
• HIL-10R
• IBD28
• IL-10 R alpha
• IL-10 receptor subunit alpha
• IL10R alpha
• IL-10R subunit 1
• IL-10R1
• IL10RA
• IL-10Ra
• IL10RIL-10R subunit alpha
• interleukin 10 receptor, alpha
• interleukin-10 receptor alpha chain
• Interleukin-10 receptor subunit 1
• interleukin-10 receptor subunit alpha

Background

CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL10RA
• Entrez:
  • 16154(Mouse)