IL-1 RII Antibody (20) [DyLight 650]

• Reactivity: Hu
• Applications: ELISA
• Clone: 20
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 650

IL-1 RII Antibody (20) [DyLight 650] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-1 RII (Met 1-Glu 343; Accession#: NP_004624.1).
• Specificity: No cross-reactivity in ELISA with:
  
  Human IL1F3 / IL1RA
  Human IL1R1 / CD121a
  Human IL1R3 / IL1RAP
  Human IL1R8 / IL1RAPL1
  Human IL1R9 / IL1RAPL2
  Human IL18R1 / CD218a
  
  Less than 10% cross-reactivity in ELISA with
  Human IL1RL1 / IL1R4 / ST2
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL1R2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-1 RII Antibody (20) [DyLight 650]

• beta
• CD121b antigen
• CD121b
• IL-1 R beta
• IL-1 RII
• IL1R2
• IL1RBCD121 antigen-like family member B
• IL-1R-beta
• IL1RII
• IL-1RII
• IL-1RT2
• IL-1RT-2
• interleukin 1 receptor, type II
• Interleukin-1 receptor beta
• MGC47725

Background

The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL1R2