IL-1 RII Products

Description

The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq)

Bioinformatics

Entrez	16178 Mouse 7850 Human
Uniprot	NM_004633 Human NM_173343 Human NP_004624 Human NP_004624.1 Human P27930 Human
Product By Gene ID	7850
Alternate Names	beta CD121b antigen CD121b IL1RBCD121 antigen-like family member B IL-1R-beta IL-1RT2 IL-1RT-2 interleukin 1 receptor, type II Interleukin-1 receptor beta MGC47725

Research Areas for IL-1 RII

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Signal Transduction