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263-2R) inhibits Recombinant Human IL-1 beta / IL-1F2 (201-LB) induced proliferation in the D10.G4.1 mouse helper T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human IL-1 beta /IL-1F2 (50 pg/mL) activity elicited by Recombinant Human IL-1 RII (2 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IL-1 RII Monoclonal Antibody (Catalog # MAB263). The ND50 is typically 2-6 µg/mL." class="big_lightbox" target="_blank">
AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108)." class="big_lightbox" target="_blank">
The protein encoded by the IL1R2 gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq)
![Neutralization IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/images/antibody/IL-1_RII_MAB263_Block_Neutralize_2208.jpg)
![Flow Cytometry IL-1 RII Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/IL-1_RII_AF563_Flow_Cytometry_10319.jpg)
![Sandwich ELISA IL-1 RII Antibody Pair [HRP]](http://images.novusbio.com/fullsize/IL-1-RII-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79441-img0001.jpg)
![Sandwich ELISA IL-1 RII Antibody Pair [HRP]](http://images.novusbio.com/fullsize/IL-1-RII-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79639-img0001.jpg)
![N/A IL-1 RII [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_IL1_RII_DR1B00_ELISA_799.jpg)
![N/A IL-1 RII [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IL1_RII_DY263_ELISA_1860.jpg)
![Immunocytochemistry IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/images/antibody/mab263_human-il-1-rii-mab-clone-32437-immunocytochemistry-20102023102849.jpg)
![Flow Cytometry IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/images/antibody/mab263_human-il-1-rii-mab-clone-32437-flow-cytometry-1052024151830..jpg)
![Immunocytochemistry/ Immunofluorescence IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/fullsize/mab263_human-il-1-rii-mab-clone-32437-812025553162.jpg)
![Immunocytochemistry/ Immunofluorescence IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/fullsize/mab263_human-il-1-rii-mab-clone-32437-8120255541737.jpg)
![Immunocytochemistry/ Immunofluorescence IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/fullsize/mab263_human-il-1-rii-mab-clone-32437-812025557284.jpg)
![Immunocytochemistry/ Immunofluorescence IL-1 RII Antibody (32437) [Unconjugated]](http://images.novusbio.com/fullsize/mab263_human-il-1-rii-mab-clone-32437-8120255534743.jpg)
![Immunohistochemistry IL-1 RII Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/IL1_RII_AF563_Immunohistochemistry_19179.jpg)
![N/A IL-1 RII [HRP]](http://images.novusbio.com/fullsize/elisa/IL-1_RII_DR1B00_ELISA_166.jpg)
