IKK alpha Antibody (4D11) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: IKK alpha Antibody (4D11) [H00001147-M01] - Analysis of monoclonal antibody to CHUK on HeLa cell . Antibody concentration 10 ug/ml.

ELISA: IKK alpha Antibody (4D11) [H00001147-M01] - Detection limit for recombinant GST tagged CHUK is 0.03 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: 4D11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

IKK alpha Antibody (4D11) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CHUK (NP_001269, 646 a.a. ~ 745 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAWLPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHLSTIIHEANEEQGNSMMNLDWSWLTE
• Localization: Cytoplasmic and Nuclear
• Specificity: CHUK - conserved helix-loop-helix ubiquitous kinase
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHUK
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IKK alpha Antibody (4D11) - Azide and BSA Free

• CHUK
• conserved helix-loop-helix ubiquitous kinaseIKBKA
• EC 2.7.11
• EC 2.7.11.10
• I-kappa-B kinase 1
• I-kappa-B kinase alpha
• IkappaB kinase
• IkBKA
• IkBKalpha
• IKK alpha
• IKK1
• IKK1I-kappa-B kinase-alpha
• IKK-A
• IKKAIkB kinase alpha subunit
• IKK-alphainhibitor of nuclear factor kappa-B kinase subunit alpha
• NFKBIKA
• NFKBIKAIKK-a kinase
• Nuclear factor NFkappaB inhibitor kinase alpha
• Nuclear factor NF-kappa-B inhibitor kinase alpha
• TCF16
• TCF-16
• Transcription factor 16

Background

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHUK
• Entrez:
  • 1147(Human)
• OMIM:
  • 600664(Human)
• Uniprot:
  • NP_001269(Human)