IGFBP-rP10/KAZALD1 Antibody

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

IGFBP-rP10/KAZALD1 Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IGFBP‑rP10
  Arg38-Tyr313
  Accession # NP_849260
• Specificity: Detects mouse IGFBP‑rP10 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: KAZALD1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IGFBP-rP10/KAZALD1 Antibody

• bone- and odontoblast-expressed gene 1
• Bono1
• FKSG28
• FKSG40
• FLJ24094
• IGFBP-related protein 10
• IGFBPrP10
• IGFBP-rP10
• KAZALD1
• Kazal-type serine peptidase inhibitor domain 1
• Kazal-type serine protease inhibitor domain 1
• kazal-type serine protease inhibitor domain-containing protein 1
• novel kazal-type serine protease inhibitor domain and immunoglobulin domain containing protein
• UNQ2945/PRO21184

Background

IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kDa secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor region, a C2-type Ig-like domain and a C-terminal poly-glu segment. An alternate variant with a 16 aa substitution for the C-terminal 33 residues has also been reported. IGFBP‑rP10 is expressed in multiple tissues including osteoblasts/odontoblasts and is up-regulated during osteoblast differentiation and bone regeneration. Mouse mature IGFBP-rP10 shares 96% and 87% aa sequence identity with rat and human IGFBP-rP10, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KAZALD1
• Uniprot:
  • NP_849260()