IGF-I R/IGF1R Antibody Pair [Biotin]

Sandwich ELISA: IGF-I R/IGF1R Antibody Pair [Biotin] [NBP2-79459] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Discontinued

IGF-I R/IGF1R Antibody Pair [Biotin] Summary

• Description: Solid Phase sandwich ELISA for the quantitative determination of Human IGF-I R/IGF1R.
• Specificity: This solid phase sandwich ELISA utilizes an antibody specific for Human IGF-I R/IGF1R.
• Standard Curve Range: 156.25-10000 pg/ml (example only; lot dependent)
• Sensitivity: 156 pg/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 ul
• Gene: IGF1R

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for IGF-I R/IGF1R Antibody Pair [Biotin]

• CD221 antigen
• CD221
• EC 2.7.10
• EC 2.7.10.1
• IGF1R
• IGF-1R
• IGF-I R
• IGF-I receptor
• IGFIR
• IGF-IR
• IGFR
• insulin-like growth factor 1 receptor
• Insulin-like growth factor I receptor
• JTK13
• MGC142170
• MGC142172
• MGC18216
• soluble IGF1R variant 1
• soluble IGF1R variant 2

Background

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: IGF1R