IGF-I R/IGF1R Products

Antibodies
IGF-I R/IGF1R Antibody (33255 ...
IGF-I R/IGF1R Antibody (33255) [Un...
Species: Hu, Mu
Applications: WB, Flow, IHC, B/N, ELISA(Cap), ICC/IF
Host: Mouse Monoclonal
IGF-I R/IGF1R Antibody [Uncon ...
IGF-I R/IGF1R Antibody [Unconjugated]
AF-305-NA
Species: Hu, Mu
Applications: WB, IHC, B/N, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
IGF-I R/IGF1R Antibody (3G5C1 ...
IGF-I R/IGF1R Antibody (3G5C1)
NB110-87052
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
ELISA Kits
Human IGF-I R/IGF1R ELISA Kit ...
Human IGF-I R/IGF1R ELISA Kit
KA2209
Species: Hu
Applications: ELISA
Lysates
IGF-I R/IGF1R Knockout HeLa C ...
IGF-I R/IGF1R Knockout HeLa Cell L...
NBP2-64650
Species: Hu
Applications: WB
IGF-I R/IGF1R Overexpression ...
IGF-I R/IGF1R Overexpression Lysate
NBL1-11867
Species: Hu
Applications: WB
Proteins
Recombinant Human IGF-I R/IGF ...
Recombinant Human IGF-I R/IGF1R Pr...
391-GR
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Human IGF-I R/IGF ...
Recombinant Human IGF-I R/IGF1R (H...
305-GR
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
IGF-I R/IGF1R Blocking Peptid ...
IGF-I R/IGF1R Blocking Peptide
NBP1-77680PEP
Species: Hu

Description

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3480
Alternate Names
  • IGF-I receptor
  • EC 2.7.10
  • Insulin-like growth factor I receptor
  • CD221 antigen
  • MGC18216
  • soluble IGF1R variant 2
  • JTK13
  • soluble IGF1R variant 1
  • IGFR
  • MGC142172
  • IGFIR
  • MGC142170
  • CD221
  • EC 2.7.10.1
  • insulin-like growth factor 1 receptor

Research Areas for IGF-I R/IGF1R

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Lipid and Metabolism
Neuroscience
Nutrient Sensing in the Brain
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

PTMs for IGF-I R/IGF1R

Learn more about PTMs related to IGF-I R/IGF1R.

Phosphorylation
Methylation
Cleavage
Demethylation
Oxidation
Ubiquitination
Glycosylation
Acetylation

Bioinformatics Tool for IGF-I R/IGF1R

Discover related pathways, diseases and genes to IGF-I R/IGF1R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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