IFN-kappa Antibody (1009725) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: IHC
• Clone: 1009725
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

IFN-kappa Antibody (1009725) [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human IFN‑ kappa
  Leu28-Lys207
  Accession # Q90W0
• Specificity: Detects human IFN‑ kappa in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from cell culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IFN-kappa Antibody (1009725) [mFluor Violet 450 SE]

• IFNK
• IFNkappa
• IFN-kappa

Background

IFN-kappa (Interferon kappa) is a secreted, nonglycosylated polypeptide that belongs to the IFN-kappa subclass of the type I interferon family of cytokines. It is expressed by macrophages in mice, and monocytes, dendritic cells and keratinocytes in human. IFN-kappa induces TNF-alpha, IL-10 and MCP-1 production by monocytes. Mouse IFN-kappa precursor is 199 amino acids (aa) in length. It contains a 21 aa signal sequence, plus a 178 aa mature region. There are two intrachain disulfide bonds plus a fifth unpaired cysteine. Mature mouse IFN-kappa (aa 22-199) shares 68% and 30% aa identity with rat and human IFN-kappa, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.