Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Mu
Applications: WB, Simple Western
Host: Sheep Polyclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Mu
Applications: Bioactivity
Description
IFN-kappa (Interferon kappa) is a secreted, nonglycosylated polypeptide that belongs to the IFN-kappa subclass of the type I interferon family of cytokines. It is expressed by macrophages in mice, and monocytes, dendritic cells and keratinocytes in human. IFN-kappa induces TNF-alpha, IL-10 and MCP-1 production by monocytes. Mouse IFN-kappa precursor is 199 amino acids (aa) in length. It contains a 21 aa signal sequence, plus a 178 aa mature region. There are two intrachain disulfide bonds plus a fifth unpaired cysteine. Mature mouse IFN-kappa (aa 22-199) shares 68% and 30% aa identity with rat and human IFN-kappa, respectively.
Bioinformatics
| Product By Gene ID |
56832 |
| Alternate Names |
|
![Western Blot IFN-kappa Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IFN-kappa_AF5206_Western_Blot_5653.jpg)
![Simple Western IFN-kappa Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/IFNkappa_AF5206_Simple_Western_17525.jpg)
![Immunohistochemistry IFN-kappa Antibody (1009725) [Unconjugated]](http://images.novusbio.com/fullsize2/IFNkappa_MAB102471_Immunohistochemistry_23605.jpg)
![Bioactivity IFN-kappa [Unconjugated]](http://images.novusbio.com/fullsize2/IFNkappa_8437MK_1036.jpg)