Universal Type I IFN Protein


There are currently no images for IFN-alpha (11200-2).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Reactivity HuSpecies Glossary

Order Details

Universal Type I IFN Protein Summary

Additional Information
(Recombinant Human IFN-alpha A/D [BglII])
Protein/Peptide Type
Recombinant Proteins


Read Publications using
11200-2 in the following applications:

Packaging, Storage & Formulations

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Universal Type I IFN Protein

  • IFNA
  • IFNA2
  • IFNA2b
  • IFNalpha
  • IFN-alpha
  • IFN-alphaA
  • INFA2
  • interferon alpha 2
  • LeIF D


Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Customers Who Viewed This Item Also Viewed...

Species: Mu
Species: Hu
Applications: BA
Species: Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu
Applications: BA
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, KO, WB
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA, S-ELISA, WB
Species: Hu
Applications: CyTOF-ready, ICC, ICFlow, KO, Simple Western, WB
Species: Hu, Mu, Rt
Applications: Flow, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: Simple Western, WB
Species: Mu
Applications: WB
Species: Hu, Mu
Applications: ChIP, Flow, PEP-ELISA, WB
Species: ET
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, Simple Western, WB

Publications for IFN-alpha (11200-2)(31)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: Bioassay, Cell Culture, In Vivo.

Filter By Application
Cell Culture
In Vivo
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 31. Show All 31 Publications.
Publications using 11200-2 Applications Species
Ikeda, T;Shimizu, R;Nasser, H;Carpenter, MA;Cheng, AZ;Brown, WL;Sauter, D;Harris, RS; APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1 mBio 2023-08-09 [PMID: 37555667] (Bioassay, Human) Bioassay Human
J Song, RD Chow, M Pena-Herna, L Zhang, SA Loeb, EY So, OD Liang, P Ren, S Chen, CB Wilen, S Lee LRRC15 inhibits SARS-CoV-2 cellular entry in trans PloS Biology, 2022-10-13;20(10):e3001805. 2022-10-13 [PMID: 36228039] (Bioassay, Human) Bioassay Human
B Los, M Preu beta ner, K Eschke, RM Vidal, A Abdelgawad, D Olofsson, S Keiper, M Paulo-Pedr, A Grindel, S Meinke, J Trimpert, F Heyd Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication Nucleic Acids Research, 2022-07-08;0(0):. 2022-07-08 [PMID: 35713540] (Bioassay, Human) Bioassay Human
X Yang, X Zhao, Y Zhu, Y Shen, Y Wang, P Lu, Z Jiang, H Pan, J Yang, J Xun, L Zhao, J Wang, Z Liang, X Shen, Y Liang, Q Lin, H Liang, L Jin, D Zhang, J Liu, B Wang, S Jiang, J Xu, H Wu, H Lu, H Zhu FKBP3 Induces Human Immunodeficiency Virus Type 1 Latency by Recruiting Histone Deacetylase 1/2 to the Viral Long Terminal Repeat MBio, 2021-07-20;0(0):e0079521. 2021-07-20 [PMID: 34281390] (Bioassay, Human) Bioassay Human
N Buang, L Tapeng, V Gray, A Sardini, C Whilding, L Lightstone, TD Cairns, MC Pickering, J Behmoaras, GS Ling, M Botto Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus Nature Communications, 2021-03-31;12(1):1980. 2021-03-31 [PMID: 33790300] (Bioassay, Human) Bioassay Human
KP Singh, JM Zerbato, W Zhao, S Braat, C Deleage, GS Tennakoon, H Mason, A Dantanaray, A Rhodes, JW Rhodes, J Torresi, AN Harman, PA Revill, M Crane, JD Estes, A Avihingsan, SR Lewin, J Audsley Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection PLoS Pathog., 2020-09-08;16(9):e1008744. 2020-09-08 [PMID: 32898182] (Bioassay, Human) Bioassay Human
C Paulus, T Harwardt, B Walter, A Marxreiter, M Zenger, E Reuschel, MM Nevels Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1 PLoS Pathog., 2020-05-04;16(5):e1008537. 2020-05-04 [PMID: 32365141] (Cell Culture, Human) Cell Culture Human
RM Van der Sl, JM Zerbato, JW Rhodes, RD Pascoe, A Solomon, NA Kumar, AI Dantanaray, S Tennakoon, J Dufloo, J McMahon, JJ Chang, VA Evans, PJ Hertzog, MR Jakobsen, AN Harman, SR Lewin, PU Cameron Diverse effects of interferon alpha on the establishment and reversal of HIV latency PLoS Pathog., 2020-02-28;16(2):e1008151. 2020-02-28 [PMID: 32109259] (Cell Culture, Human) Cell Culture Human
E Kuca-Warna, U Skalska, I Janicka, U Musia?owic, K Bonek, P G?uszko, P Szcz?sny, M Olesi?ska, E Kontny The Phenotype and Secretory Activity of Adipose-Derived Mesenchymal Stem Cells (ASCs) of Patients with Rheumatic Diseases Cells, 2019-12-17;8(12):. 2019-12-17 [PMID: 31861245] (Cell Culture, Human) Cell Culture Human
F Vahedi, AJ Lee, SE Collins, MV Chew, E Lusty, B Chen, A Dubey, CD Richards, JJ Feld, RS Russell, KL Mossman, AA Ashkar IL-15 and IFN-? signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling Cytokine, 2018-06-19;0(0):. 2018-06-19 [PMID: 29908921] (Bioassay, Human) Bioassay Human
Show All 31 Publications.

Reviews for IFN-alpha (11200-2) (0)

There are no reviews for IFN-alpha (11200-2). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for IFN-alpha (11200-2) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional IFN-alpha Products

Diseases for IFN-alpha (11200-2)

Discover more about diseases related to IFN-alpha (11200-2).

Pathways for IFN-alpha (11200-2)

View related products by pathway.

PTMs for IFN-alpha (11200-2)

Learn more about PTMs related to IFN-alpha (11200-2).

Blogs on IFN-alpha.

STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also ...  Read full blog post.

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our Universal Type I IFN Protein and receive a gift card or discount.


Gene Symbol IFNA2