Hyaluronidase 1/HYAL1 Antibody (2H7)

Immunoprecipitation: Hyaluronidase 1/HYAL1 Antibody (2H7) [H00003373-M01] - Analysis of HYAL1 transfected lysate using anti-HYAL1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HYAL1 MaxPab rabbit polyclonal antibody.

Sandwich ELISA: Hyaluronidase 1/HYAL1 Antibody (2H7) [H00003373-M01] - Detection limit for recombinant GST tagged HYAL1 is approximately 1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA, IP, S-ELISA
• Clone: 2H7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Hyaluronidase 1/HYAL1 Antibody (2H7) Summary

• Immunogen: HYAL1 (NP_009296, 60 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQH
• Specificity: HYAL1 (2H7)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: HYAL1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Sandwich ELISA
• Application Notes: Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Hyaluronidase 1/HYAL1 Antibody (2H7)

• EC 3.2.1.35
• FUS2
• HYAL1
• HYAL-1
• Hyaluronidase 1
• Hyaluronoglucosaminidase 1
• hyaluronoglucosaminidase-1
• LUCA1
• luCa-1
• LUCA1hyaluronidase-1
• Lung carcinoma protein 1
• MGC45987
• NAT6
• plasma hyaluronidase
• tumor suppressor LUCA-1

Background

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HYAL1
• Entrez:
  • 3373(Human)
• OMIM:
  • 601492(Human)