HVEM/TNFRSF14 Antibody

Images

 
Western Blot: HVEM/TNFRSF14 Antibody [NBP1-76690] - Analysis of 125 ng of TNFRSF14 with TNFRSF14 antibody at 1 ug/mL.
Immunohistochemistry-Paraffin: HVEM/TNFRSF14 Antibody [NBP1-76690] - Mouse thymus tissue with TNFRSF14 antibody at 1 ug/ml.
Western Blot: HVEM/TNFRSF14 Antibody [NBP1-76690] - Mouse thymus tissue lysate with TNFRSF14 antibody at (A) 1 and (B) 2 u/mL.
Immunofluorescence: HVEM/TNFRSF14 Antibody [NBP1-76690] - Mouse Thymus tissue with TNFRSF14 antibody at 10 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

HVEM/TNFRSF14 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TNFRSF14. The immunogen is located within amino acids 20 - 70 of TNFRSF14. Amino Acid Squence: PSCREDEYPVGSECC
Specificity
Multiple isoforms of TNFRSF14 are known to exist.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNFRSF14
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1 ug/ml
  • Immunohistochemistry-Paraffin 1 ug/ml
  • Immunofluorescence 10 ug/ml
Theoretical MW
23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
HVEM/TNFRSF14 Peptide (NBP1-76690PEP)
Publications
Read Publication using NBP1-76690.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for HVEM/TNFRSF14 Antibody

  • ATAR
  • CD270 antigen
  • CD270
  • CD40-like protein
  • Herpes virus entry mediator A
  • Herpesvirus entry mediator A
  • HveA
  • HVEM
  • HVEMTR2HVEAATAR
  • LIGHTR
  • TNFRSF14
  • tumor necrosis factor receptor superfamily member 14
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entrymediator)
  • Tumor necrosis factor receptor-like 2
  • tumor necrosis factor receptor-like gene2

Background

Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappaB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HVEM/TNFRSF14 Antibody (NBP1-76690)(1)

We have publications tested in 1 confirmed species: Human.


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Bioinformatics

Gene Symbol TNFRSF14
Uniprot