HVEM/TNFRSF14 Antibody - BSA Free

Western Blot: HVEM/TNFRSF14 Antibody [NBP1-76689] - Raji cell lysate with TNFRSF14 antibody at 2 u/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry/ Immunofluorescence: HVEM/TNFRSF14 Antibody - BSA Free [NBP1-76689] - Immunofluorescence of HVEM/TNFRSF14 in Raji cells with HVEM/TNFRSF14 antibody at 20 u/mL.

Immunocytochemistry/ Immunofluorescence: HVEM/TNFRSF14 Antibody - BSA Free [NBP1-76689] - Immunocytochemistry of HVEM/TNFRSF14 in Raji with HVEM/TNFRSF14 antibody at 10 u/mL.

Western Blot: HVEM/TNFRSF14 Antibody - BSA Free [NBP1-76689] - Western blot analysis of 5 ng of HVEM/TNFRSF14 with HVEM/TNFRSF14 antibody at 1 ug/mL.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

HVEM/TNFRSF14 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit HVEM/TNFRSF14 Antibody - BSA Free (NBP1-76689) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TNFRSF14. The immunogen is located within the last 50 amino acids of TNFRSF14. Amino Acid Squence: VQRKRQEAEGEATVIE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TNFRSF14
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 10-20 ug/ml
  • Western Blot 2 ug/ml
• Control Peptide:

  HVEM/TNFRSF14 Peptide (NBP1-76689PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for HVEM/TNFRSF14 Antibody - BSA Free

• ATAR
• CD270 antigen
• CD270
• CD40-like protein
• Herpes virus entry mediator A
• Herpesvirus entry mediator A
• HveA
• HVEM
• HVEMTR2HVEAATAR
• LIGHTR
• TNFRSF14
• tumor necrosis factor receptor superfamily member 14
• tumor necrosis factor receptor superfamily, member 14 (herpesvirus entrymediator)
• Tumor necrosis factor receptor-like 2
• tumor necrosis factor receptor-like gene2

Background

Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappaB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF14
• Uniprot:
  • Q92956()