VEGF-C Products

Antibodies
VEGF-C Antibody [Unconjugated ...
VEGF-C Antibody [Unconjugated]
AF752
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
VEGF-C Antibody
VEGF-C Antibody
NB110-61022
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
VEGF-C ELISA Kit [HRP]
VEGF-C ELISA Kit [HRP]
KA0173
Species: Hu
VEGF-C ELISA Kit [Biotin]
VEGF-C ELISA Kit [Biotin]
NBP1-92698
Lysates
VEGF-C Overexpression Lysate ...
VEGF-C Overexpression Lysate (Native)
NBP2-04293
Applications: WB
Proteins
VEGF-C Recombinant Protein
VEGF-C Recombinant Protein
NBP2-52309
Species: Hu
Applications: PAGE
VEGF-C Recombinant Protein
VEGF-C Recombinant Protein
NBP1-99434
Species: Rt
VEGF-C Recombinant Protein
VEGF-C Recombinant Protein
NBP1-99429
Species: Hu
RNAi
VEGF-C RNAi
VEGF-C RNAi
H00007424-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. The human VEGFC gene is located on chromosome 4q34.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 7424
Alternate Names
  • Flt4-L
  • Flt4 ligand
  • Vascular endothelial growth factor-related protein
  • VRPFLT4 ligand DHM
  • VEGF-C
  • vascular endothelial growth factor C

Research Areas for VEGF-C

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
HIF Target Genes
Hypoxia

PTMs for VEGF-C

Learn more about PTMs related to VEGF-C.

Phosphorylation
Cleavage
Methylation
Demethylation

Bioinformatics Tool for VEGF-C

Discover related pathways, diseases and genes to VEGF-C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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