Human sTNF RII/TNFRSF1B Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Catalog# & Conjugate Size Price

Human sTNF RII/TNFRSF1B Quantikine ELISA Kit Summary

Background
The Quantikine Human sTNF RII Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure human sTNF RII in cell culture supernates, serum, plasma, or urine. It contains E. coli-expressed recombinant human sTNF RII as well as antibodies raised against this polypeptide. The recombinant protein represents the non-glycosylated, N-terminal methionyl form of the naturally occu...rring human soluble Type II receptor for TNF, minus 53 amino acids from the proline-rich region of the protein just exterior to the transmembrane domain, with an apparent molecular weight of approximately 19.8 kDa. This immunoassay has been shown to accurately quantitate the recombinant soluble sTNF RII. Results obtained using natural sTNF RII showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural sTNF RII. Since the measurement of human sTNF RII by this immunoassay is insensitive to added TNF-alpha or TNF-beta, it is probable that this measurement corresponds to the total amount of the soluble receptor present in samples, (i.e. the total amount of free receptor plus the total amount of receptor bound to TNF).
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Specificity
Natural and recombinant human sTNF RII
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
TNFRSF1B

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DRT200.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human sTNF RII/TNFRSF1B Quantikine ELISA Kit

  • CD120b antigen
  • CD120b
  • Etanercept
  • p75 TNF receptor
  • p75TBPII
  • p75TNFR
  • soluble TNFR1B variant 1
  • TNF RII
  • TNFBRp80 TNF-alpha receptor
  • TNF-R2
  • TNFR2TNFR1B
  • TNF-R75
  • TNFR80
  • TNFRII
  • TNF-RII
  • TNF-R-II
  • TNFR-II
  • TNFRSF1B
  • tumor necrosis factor beta receptor
  • tumor necrosis factor binding protein 2
  • Tumor necrosis factor receptor 2
  • tumor necrosis factor receptor superfamily member 1B
  • tumor necrosis factor receptor superfamily, member 1B
  • Tumor necrosis factor receptor type II

Background

TNF RII (Tumor Necrosis Factor Receptor II), also known as TNFRSF1B, p75/p80, and CD120b, is a widely expressed receptor for membrane-associated TNF-alpha and Lymphotoxin-alpha. Its activation initiates pro-inflammatory and pro-survival responses via NFkB-dependent signaling pathways, although it may also induce apoptosis.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for TNF RII/TNFRSF1B (DRT200)(60)

We have publications tested in 5 confirmed species: Human, Primate - Cholrocebus pygerythrus (Vervet Monkey), Primate - Macaca mulatta (Rhesus Macaque), Primate - Papio cynocephalus (Yellow Baboon), Primate - Papio hamadryas (Hamadyras Baboon).


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Human
(56)
Primate - Cholrocebus pygerythrus (Vervet Monkey)
(1)
Primate - Macaca mulatta (Rhesus Macaque)
(1)
Primate - Papio cynocephalus (Yellow Baboon)
(1)
Primate - Papio hamadryas (Hamadyras Baboon)
(1)
All Species
Showing Publications 1 - 10 of 60. Show All 60 Publications.
Publications using DRT200 Applications Species
BT Cleland, P Papanek, BA Ingraham, A Harkins, M Garnier-Vi, D Woo, ME Csuka, A V Ng Determinants of low bone mineral density in people with multiple sclerosis: Role of physical activity Mult Scler Relat Disord, 2019;38(0):101864. 2019 [PMID: 31801106] (Human) Human
V Cantón-Hab, MDP Carrera-Go, MT Moreno-Cas, JM Quesada-Gó, M Rich-Ruiz Correlation between biomarkers of pain in saliva and PAINAD scale in elderly people with cognitive impairment and inability to communicate: descriptive study protocol BMJ Open, 2019;9(11):e032927. 2019 [PMID: 31712347] (Human) Human
FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk, Systemic Inflammation Precedes Microalbuminuria in Diabetes Kidney Int Rep, 2019;4(10):1373-1386. 2019 [PMID: 31701047] (Human) Human
R Grzanka, A Damasiewic, A Kasperska- Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria Allergy Asthma Clin Immunol, 2019;15(0):15. 2019 [PMID: 30911316] (Human) Human
H Yogasundar, A Nikhanj, BN Putko, M Boutin, S Jain-Ghai, A Khan, C Auray-Blai, ML West, GY Oudit Elevated Inflammatory Plasma Biomarkers in Patients With Fabry Disease: A Critical Link to Heart Failure With Preserved Ejection Fraction J Am Heart Assoc, 2018;7(21):e009098. 2018 [PMID: 30571380] (Human) Human
A Babic, N Schnure, NP Neupane, MM Zaman, N Rifai, MW Welch, LK Brais, DA Rubinson, V Morales-Oy, C Yuan, S Zhang, EM Poole, BM Wolpin, MH Kulke, DA Barbie, K Wong, CS Fuchs, K Ng Plasma inflammatory cytokines and survival of pancreatic cancer patients Clin Transl Gastroenterol, 2018;9(4):145. 2018 [PMID: 29691365] (Human) Human
N Kudo, H Yamamori, T Ishima, K Nemoto, Y Yasuda, M Fujimoto, H Azechi, T Niitsu, S Numata, M Ikeda, M Iyo, T Ohmori, M Fukunaga, Y Watanabe, K Hashimoto, R Hashimoto Plasma Levels of Soluble Tumor Necrosis Factor Receptor 2 (sTNFR2) are Associated with Hippocampal Volume and Cognitive Performance in Patients with Schizophrenia Int. J. Neuropsychopharmacol., 2018;0(0):. 2018 [PMID: 29529289] (Human) Human
LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa Reevaluation of immune activation in the era of cART and an aging HIV-infected population JCI Insight, 2017;2(20):. 2017 [PMID: 29046481] (Human) Human
S Faridi, K Naddafi, H Kashani, R Nabizadeh, M Alimohamma, F Momeniha, S Faridi, S Niazi, A Zare, A Gholampour, M Hoseini, Z Pourpak, MS Hassanvand, M Yunesian Bioaerosol exposure and circulating biomarkers in a panel of elderly subjects and healthy young adults Sci. Total Environ, 2017;593(0):380-389. 2017 [PMID: 28351806] (Human) Human
T Gohda, S Maruyama, N Kamei, S Yamaguchi, T Shibata, M Murakoshi, S Horikoshi, Y Tomino, I Ohsawa, H Gotoh, S Nojiri, Y Suzuki Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis Sci Rep, 2017;7(0):43520. 2017 [PMID: 28256549] (Human) Human
Show All 60 Publications.

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Product General Protocols

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FAQs for TNF RII/TNFRSF1B (DRT200). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DRT200
HRP DRT200
HRP DRT200

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Bioinformatics

Gene Symbol TNFRSF1B