Human Osteocalcin DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Osteocalcin DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Osteocalcin DuoSet ELISA, 5 Plate

• BGLAP
• BGP
• bone gamma-carboxyglutamate (gla) protein (osteocalcin)
• bone gamma-carboxyglutamate (gla) protein
• Bone Gla protein
• Gamma-carboxyglutamic acid-containing protein
• OC
• OCN
• Osteocalcin

Background

Osteocalcin, also named Bone gamma-carboxyglutamic Acid Protein, is a secreted protein whose expression is restricted to cells of the osteoblast lineage. It has been frequently used as a marker for osteoblast lineage cells.

Publications for Osteocalcin (DY1419-05)(12)

Publications using DY1419-05

• Shin, YJ;Ma, X;Joo, MK;Baek, JS;Kim, DH; Lactococcus lactis and Bifidobacterium bifidum alleviate postmenopausal symptoms by suppressing NF-?B signaling and microbiota dysbiosis Scientific reports 2024-12-30 [PMID: 39738244] (Mouse)
• Jiang, J;Röper, L;Fuchs, F;Hanschen, M;Failer, S;Alageel, S;Cong, X;Dornseifer, U;Schilling, AF;Machens, HG;Moog, P; Bone Regenerative Effect of Injectable Hypoxia Preconditioned Serum-Fibrin (HPS-F) in an Ex Vivo Bone Defect Model International journal of molecular sciences 2024-05-13 [PMID: 38791352] (Human)
• Rehage, E;Sowislok, A;Busch, A;Papaeleftheriou, E;Jansen, M;Jäger, M; Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro International journal of molecular sciences 2023-11-01 [PMID: 37958857] (Human)
• Martín-Núñez, E;Goñi-Olóriz, M;Matilla, L;Garaikoetxea, M;Mourino-Alvarez, L;Navarro, A;Fernández-Celis, A;Tamayo, I;Gainza, A;Álvarez, V;Sádaba, R;Barderas, MG;Jover, E;López-Andrés, N; Influence of diabetes mellitus on the pathological profile of aortic stenosis: a sex-based approach Cardiovascular diabetology 2023-10-17 [PMID: 37848892] (Human)
• Kurzyk, A;Szwed-Georgiou, A;Pagacz, J;Antosik, A;Tymowicz-Grzyb, P;Gerle, A;Szterner, P;W?odarczyk, M;P?oci?ski, P;Urbaniak, MM;Rudnicka, K;Biernat, M; Calcination and ion substitution improve physicochemical and biological properties of nanohydroxyapatite for bone tissue engineering applications Scientific reports 2023-09-16 [PMID: 37717040] (Human)
• Skelton, AM;Cohen, DJ;Boyan, BD;Schwartz, Z; Osteoblast-Derived Matrix Vesicles Exhibit Exosomal Traits and a Unique Subset of microRNA: Their Caveolae-Dependent Endocytosis Results in Reduced Osteogenic Differentiation International journal of molecular sciences 2023-08-14 [PMID: 37628952] (Human)
• Paramasivam, S;Perumal, SS; Methanolic extract of O.umbellata L. exhibits anti-osteoporotic effect via promoting osteoblast proliferation in MG-63�cells and inhibiting osteoclastogenesis in RANKL-stimulated RAW 264.7�cells Journal of ethnopharmacology 2023-05-24 [PMID: 37236379] (Human)
• N Xia, Y Cai, W Wang, C Bao, Y Li, Q Xie, W Xu, D Liu Association of bone-related�biomarkers with femoral neck bone strength Bmc Musculoskeletal Disorders, 2022-05-21;23(1):482. 2022-05-21 [PMID: 35597928] (Human)
• M Kim, M Park The Brown Algae Ishige sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis through Downregulation of NFATc1/c-Fos Nutrients, 2022-04-19;14(9):. 2022-04-19 [PMID: 35565651] (Rat)
• M Vadana, S Cecoltan, L Ciortan, RD Macarie, AC Mihaila, MM Tucureanu, AM Gan, M Simionescu, I Manduteanu, I Droc, E Butoi Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells International Journal of Molecular Sciences, 2022-03-29;23(7):. 2022-03-29 [PMID: 35409134] (Human)
• JW Park, Y Tsutsumi, EK Park Osteogenic Differentiation of Human Mesenchymal Stem Cells Modulated by Surface Manganese Chemistry in SLA Titanium Implants BioMed Research International, 2022-01-13;2022(0):5339090. 2022-01-13 [PMID: 35071596] (Human)
• Z Li, J Zheng, D Wan, X Yang Uniaxial Static Strain Promotes Osteoblast Proliferation and Bone Matrix Formation in Distraction Osteogenesis In Vitro Biomed Res Int, 2020-08-12;2020(0):3906426. 2020-08-12 [PMID: 32855965] (Rat)

FAQs for Osteocalcin (DY1419-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.