Human Epiregulin DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Epiregulin DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Epiregulin DuoSet ELISA, 5 Plate

• Epiregulin
• ER
• EREG
• proepiregulin

Background

Epiregulin is a member of the EGF family of growth factors which includes, among others, epidermal growth factor (EGF), Transforming Growth Factor (TGF)-alpha, Amphiregulin (AR), HB (heparin-binding)-EGF, Betacellulin (BTC), and the various heregulins (HRGs). The mode of action of Epiregulin is similar to other EGF family members in that it binds to and activates the tyrosine-kinase, ErbB family receptors (ErbB1 through B4).

Publications for Epiregulin (DY1195-05)(5)

Publications using DY1195-05

• Sperrhacke, M;Leitzke, S;Ahrens, B;Reiss, K; Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis Membranes 2023-08-05 [PMID: 37623781] (Human)
• M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts International Journal of Molecular Sciences, 2022-09-08;23(18):. 2022-09-08 [PMID: 36142285] (Human)
• S Ghosh, NB Nataraj, A Noronha, S Patkar, A Sekar, S Mukherjee, S Winograd-K, L Kramarski, A Verma, M Lindzen, DD Garcia, J Green, G Eisenberg, H Gil-Henn, A Basu, Y Lender, S Weiss, M Oren, M Lotem, B Geiger, E Ruppin, Y Yarden PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR Cell Reports, 2021-05-25;35(8):109181. 2021-05-25 [PMID: 34038737] (Human)
• M Lindzen, S Ghosh, A Noronha, D Drago, NB Nataraj, O Leitner, S Carvalho, E Zmora, S Sapoznik, KB Shany, K Levanon, D Aderka, BS Ramírez, M Dahlhoff, I McNeish, Y Yarden Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53 Oncogene, 2021-04-30;0(0):. 2021-04-30 [PMID: 33941851] (Human)
• W Cao, LL Luo, WW Chen, L Liang, RR Zhang, YL Zhao, J Chen, J Yue Polymorphism in the EREG gene confers susceptibility to tuberculosis BMC Med. Genet., 2019-01-11;20(1):7. 2019-01-11 [PMID: 30634928] (Human)