Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Species: Hu
Applications: WB, B/N
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA(Cap)
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Pm-Cm
Applications: Bioactivity
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
DcR3 belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
8771 |
| Alternate Names |
- DCR3Decoy receptor for Fas ligand
- Decoy receptor 3
- M68DJ583P15.1.1
- TR6DcR3
- tumor necrosis factor receptor superfamily member 6B
- tumor necrosis factor receptor superfamily, member 6b, decoy
|
![N/A DcR3/TNFRSF6B [Biotin]](http://images.novusbio.com/fullsize2/DATA_DcR3_DY142_ELISA_1644.jpg)
![Bioactivity DcR3/TNFRSF6B [Unconjugated]](http://images.novusbio.com/fullsize2/DcR3_9297DC_1434.jpg)
