DcR3/TNFRSF6B Products

Description

DcR3 belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

Bioinformatics

Entrez	8771 Human
Uniprot	NM_032945 Human NP_003814 Human O95407 Human
Product By Gene ID	8771
Alternate Names	DCR3Decoy receptor for Fas ligand Decoy receptor 3 M68DJ583P15.1.1 TR6DcR3 tumor necrosis factor receptor superfamily member 6B tumor necrosis factor receptor superfamily, member 6b, decoy

Research Areas for DcR3/TNFRSF6B

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Biology
Cytokine Research
Immunology
Innate Immunity