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DcR3/TNFRSF6B Products

Antibodies
DcR3/TNFRSF6B Antibody
DcR3/TNFRSF6B Antibody
AF142
CTS013). Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the membrane of epithelial cells in gastric glands. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry DcR3/TNFRSF6B Antibody
MAB050), Recombinant Human DcR3/TNFRSF6B Fc Chimera (Catalog # 142-DC) inhibits Recombinant Human Fas Ligand/TNFSF6 (Catalog # 126-FL) induced apoptosis in the Jurkat human acute T cell leukemia cell line in a dose-dependent manner (orange line). Under these conditions, inhibition of Recombinant Human Fas Ligand/TNFSF6 (2 ng/mL) activity elicited by Recombinant Human DcR3/TNFRSF6B Fc Chimera (50 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human DcR3/TNFRSF6B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF142). The ND50 is typically 0.1-0.5 µg/mL." class="big_lightbox" target="_blank"> Neutralization DcR3/TNFRSF6B Antibody
Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
DcR3/TNFRSF6B Antibody (22981 ...
DcR3/TNFRSF6B Antibody (229812)
MAB2135
MAB050), Recombinant Human DcR3/TNFRSF6B Fc Chimera (Catalog # 142-DC) inhibits Recombinant Human Fas Ligand/TNFSF6 (Catalog # 126-FL) induced apoptosis in the Jurkat human acute T cell leukemia cell line in a dose-dependent manner (orange line). Under these conditions, inhibition of Recombinant Human Fas Ligand/TNFSF6 (20 ng/mL) activity elicited by Recombinant Human DcR3/TNFRSF6B Fc Chimera (1 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human DcR3/TNFRSF6B Monoclonal Antibody (Catalog # MAB2135). The ND50 is typically 0.1-0.4 µg/mL." class="big_lightbox" target="_blank"> Neutralization DcR3/TNFRSF6B Antibody (229812)
142-DC) was serially diluted and captured by Mouse Anti-Human DcR3/TNFRSF6B Monoclonal Antibody (Catalog # MAB21351) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human DcR3/TNFRSF6B Monoclonal Antibody (Catalog # MAB2135) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA DcR3/TNFRSF6B Antibody (229812)
Species: Hu
Applications: WB, B/N
Host: Mouse Monoclonal
DcR3/TNFRSF6B Antibody (22981 ...
DcR3/TNFRSF6B Antibody (229817)
MAB21351
142-DC) was serially diluted and captured by Mouse Anti-Human DcR3/TNFRSF6B Monoclonal Antibody (Catalog # MAB21351) coated on a Clear Polystyrene Microplate (Catalog # DY990). Mouse Anti-Human DcR3/TNFRSF6B Monoclonal Antibody (Catalog # MAB2135) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA DcR3/TNFRSF6B Antibody (229817)
Species: Hu
Applications: WB, ELISA(Cap)
Host: Mouse Monoclonal
ELISA Kits
Human DcR3/TNFRSF6B DuoSet EL ...
Human DcR3/TNFRSF6B DuoSet ELISA, ...
DY142
Species: Hu
Applications: ELISA
Lysates
DcR3/TNFRSF6B Overexpression ...
DcR3/TNFRSF6B Overexpression Lysate
NBL1-17158
Species: Hu
Applications: WB
DcR3/TNFRSF6B Overexpression ...
DcR3/TNFRSF6B Overexpression Lysate
NBP2-11314
Species: Hu
Applications: WB
Proteins
Recombinant Human DcR3/TNFRSF ...
Recombinant Human DcR3/TNFRSF6B Fc...
142-DC
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Cynomolgus DcR3/T ...
Recombinant Cynomolgus DcR3/TNFRSF...
9297-DC
Species: Pm-Cm
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human DcR3/TNFRSF ...
Recombinant Human DcR3/TNFRSF6B Hi...
NBP2-22907
Species: Hu
Applications: PAGE

Description

DcR3 belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 8771
Alternate Names
  • DCR3Decoy receptor for Fas ligand
  • Decoy receptor 3
  • M68DJ583P15.1.1
  • TR6DcR3
  • tumor necrosis factor receptor superfamily member 6B
  • tumor necrosis factor receptor superfamily, member 6b, decoy

Research Areas for DcR3/TNFRSF6B

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Biology
Cytokine Research
Immunology
Innate Immunity