Human CXCL11/I-TAC DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CXCL11/I-TAC DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CXCL11

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL11/I-TAC DuoSet ELISA, 15 Plate

• beta-R1
• b-R1
• chemokine (C-X-C motif) ligand 11
• CXCL11
• H174
• H174IP9
• Interferon gamma-inducible protein 9
• Interferon-inducible T-cell alpha chemoattractant
• IP-9member 11
• ITAC
• I-TAC
• I-TACMGC102770
• SCYB9B
• small inducible cytokine subfamily B (Cys-X-Cys), member 9B
• Small-inducible cytokine B11

Background

Interferon-inducible T cell a chemoattractant (I-TAC), also known as SCYB9B, H174 and beta-R1, is a non-ELR motif-containing CXC chemokine. I-TAC shares 36% and 37% amino acid sequence homology with IP-10 and MIG , respectively. I-TAC is expressed at low levels in normal tissues, including thymus, spleen and pancreas.

Publications for CXCL11/I-TAC (DY672)(17)

Publications using DY672

• Green, HLH;Sum, H;Sinha, P;Visnagri, A;Lee, SH;Baffour-Kyei, A;Lee, H;Santos, F;Theofilatos, K;Brewer, AC; TET2 has endothelial-specific roles in interferon responses that are dysregulated by hyperglycaemia in vitro and in vivo The Journal of biological chemistry 2025-07-25 [PMID: 40716745] (Human)
• E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells International Journal of Molecular Sciences, 2022-04-20;23(9):. 2022-04-20 [PMID: 35562961] (Human)
• L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis Stem Cells International, 2021-07-27;2021(0):9929461. 2021-07-27 [PMID: 34354753] (Human)
• HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration Frontiers in Pharmacology, 2021-05-13;12(0):679741. 2021-05-13 [PMID: 34054553] (Human)
• GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation Biomolecules, 2021-02-21;11(2):. 2021-02-21 [PMID: 33669910] (Human)
• H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 2021-01-21;11(1):1949. 2021-01-21 [PMID: 33479269] (Human)
• H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 2020-12-08;11(0):598702. 2020-12-08 [PMID: 33363471] (Human)
• M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features PLoS ONE, 2020-11-02;15(11):e0241719. 2020-11-02 [PMID: 33137121] (Human)
• JA Woznicki, P Flood, M Bustamante, P Stamou, G Moloney, A Fanning, SA Zulquernai, J McCarthy, F Shanahan, S Melgar, K Nally Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-gamma and TNF-alpha in intestinal epithelial cells Cell Death Dis, 2020-01-27;11(1):68. 2020-01-27 [PMID: 31988296] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo IL-27 Modulates Chemokine Production in TNF-? -Stimulated Human Oral Epithelial Cells Cell. Physiol. Biochem., 2017-10-05;43(3):1198-1206. 2017-10-05 [PMID: 28977795] (Human)
• JP Strassner, M Rashighi, M Ahmed Refa, JM Richmond, JE Harris Suction blistering the lesional skin of vitiligo patients reveals useful biomarkers of disease activity J. Am. Acad. Dermatol, 2017-03-01;0(0):. 2017-03-01 [PMID: 28259440] (Human)
• Fenwick P, Macedo P, Kilty I, Barnes P, Donnelly L Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells. PLoS ONE, 2015-06-19;10(6):e0128757. 2015-06-19 [PMID: 26090665] (Human)
• Byung Min Chung, Artem Arutyunov, Erika Ilagan, Nu Yao, Marsha Wills-Karp, Pierre A. Coulombe Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes Journal of Cell Biology 2015-03-02 [PMID: 25713416] (Human)
• Manousou P, Kolios G, Drygiannakis I, Koulentaki M, Pyrovolaki K, Voumvouraki A, Notas G, Bourikas L, Papadaki H, Kouroumalis E CXCR3 axis in patients with primary biliary cirrhosis: a possible novel mechanism of the effect of ursodeoxycholic acid. Clin Exp Immunol, 2013-04-01;172(1):9-15. 2013-04-01 [PMID: 23480180] (Human)
• Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation. Nat. Med., 2008-02-03;14(2):199-204. 2008-02-03 [PMID: 18246079] (Mouse)
• Tudhope SJ, Catley MC, Fenwick PS, Russell RE, Rumsey WL, Newton R, Barnes PJ, Donnelly LE The role of IkappaB kinase 2, but not activation of NF-kappaB, in the release of CXCR3 ligands from IFN-gamma-stimulated human bronchial epithelial cells. J. Immunol., 2007-11-01;179(9):6237-45. 2007-11-01 [PMID: 17947699] (Human)
• Curbishley SM, Eksteen B, Gladue RP, Lalor P, Adams DH CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow. Am. J. Pathol., 2005-09-01;167(3):887-99. 2005-09-01 [PMID: 16127166] (Human)

FAQs for CXCL11/I-TAC (DY672). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CXCL11