Human Cathepsin L DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Cathepsin L DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CTSL

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Cathepsin L DuoSet ELISA, 15 Plate

• Cathepsin L
• cathepsin L1
• CATL
• CTSL
• CTSL1
• CTSLEC 3.4.22.15
• EC 3.4.22
• FLJ31037
• Major excreted protein
• MEP

Background

Cathepsin L is a lysosomal cysteine protease expressed in most eukaryotic cells. Cathepsin L is known to hydrolyze a number of proteins, including the proform of urokinase-type plasminogen activator, which is activated by Cathepsin L cleavage. Cathepsin L has also been shown to proteolytically inactivate a1-antitrypsin and secretory leucoprotease inhibitor, two major protease inhibitors of the respiratory tract.

Publications for Cathepsin L (DY952)(6)

Publications using DY952

• Tsao, LC;Wang, JS;Ma, X;Sodhi, S;Ragusa, JV;Liu, B;McBane, J;Wang, T;Wei, J;Liu, CX;Yang, X;Lei, G;Spasojevic, I;Fan, P;Trotter, TN;Morse, M;Lyerly, HK;Hartman, ZC; Effective extracellular payload release and immunomodulatory interactions govern the therapeutic effect of trastuzumab deruxtecan (T-DXd) Nature communications 2025-04-02 [PMID: 40175391] (Human)
• M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)
• M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)
• I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)
• Rai S, Nejadhamzeeigilani Z, Gutowski N, Whatmore J Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium. J Exp Clin Cancer Res, 2015-09-25;34(0):105. 2015-09-25 [PMID: 26407999] (Human)
• Zhang Q, Wang W, Li J, Yang N, Chen G, Wang Z, Liang Z Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage. Acta Pharmacol Sin, 2015-06-22;36(9):1113-25. 2015-06-22 [PMID: 26095040] (Human)

FAQs for Cathepsin L (DY952). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: CTSL