Human Activin A DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Activin A DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: INHBA

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Activin A DuoSet ELISA, 15 Plate

• Activin A
• activin AB alpha polypeptide
• Activin beta-A chain
• erythroid differentiation factor
• Erythroid differentiation protein
• follicle-stimulating hormone-releasing protein
• FSH-releasing protein
• inhibin beta A chain
• inhibin beta A subunit
• Inhibin, beta-1

Background

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. Activin isoforms and other members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction.

Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. Five beta subunits (mammalian beta A, beta B, beta C, beta E and Xenopus beta D) have been cloned to date. The activin/inhibin nomenclature reflects the subunit composition of the proteins: Activin A (beta A - beta A), Activin B (beta B - beta B), Activin AB (beta A - beta B), Inhibin A (alpha - beta A) and Inhibin B (alpha - beta B).

Publications for Activin A (DY338)(17)

Publications using DY338

• Livshits, G;Tarabeih, N;Kalinkovich, A;Shalata, A;Ashkenazi, S; Metabolic and Inflammatory Biomarkers Predicting Sarcopenic Obesity and Cardiometabolic Risk in Arab Women: A Cross-Sectional Study International journal of molecular sciences 2025-06-13 [PMID: 40565161] (Human)
• Tarabeih, N;Kalinkovich, A;Shalata, A;Higla, O;Livshits, G; Pro-Inflammatory Biomarkers Combined with Body Composition Display a Strong Association with Knee Osteoarthritis in a Community-Based Study Biomolecules 2023-08-28 [PMID: 37759715] (Human)
• Baccouche, B;Lietuvninkas, L;Kazlauskas, A; Activin A Limits VEGF-Induced Permeability via VE-PTP International journal of molecular sciences 2023-05-12 [PMID: 37240047] (Human)
• S Hamalian, R Güth, F Runa, F Sanchez, E Vickers, M Agajanian, J Molnar, T Nguyen, J Gamez, JD Humphries, A Nayak, MJ Humphries, J Tchou, IK Zervantona, JA Kelber A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers Oncogene, 2021-07-08;0(0):. 2021-07-08 [PMID: 34239043] (Human)
• C Veraar, J Kliman, A Benazzo, F Oberndorfe, M Laggner, P Hacker, T Raunegger, S Janik, P Jaksch, W Klepetko, HJ Ankersmit, B Moser Potential novel biomarkers for chronic lung allograft dysfunction and azithromycin responsive allograft dysfunction Scientific Reports, 2021-03-24;11(1):6799. 2021-03-24 [PMID: 33762606] (Human)
• HK Pihlstrøm, T Ueland, AE Michelsen, P Aukrust, F Gatti, C Hammarströ, M Kasprzycka, J Wang, G Haraldsen, G Mjøen, DO Dahle, K Midtvedt, IA Eide, A Hartmann, H Holdaas Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients PLoS ONE, 2020-12-16;15(12):e0243759. 2020-12-16 [PMID: 33326471] (Human)
• A Radujkovic, T Boch, F Nolte, D Nowak, C Kunz, A Gieffers, C Müller-Tid, P Dreger, WK Hofmann, T Luft Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile Cancers, 2020-12-08;12(12):. 2020-12-08 [PMID: 33302451] (Human)
• S Janik, C Bekos, P Hacker, T Raunegger, AI Schiefer, L Müllauer, C Veraar, B Dome, W Klepetko, HJ Ankersmit, B Moser Follistatin impacts Tumor Angiogenesis and Outcome in Thymic Epithelial Tumors Sci Rep, 2019-11-22;9(1):17359. 2019-11-22 [PMID: 31757999] (Human)
• C Roudebush, A Catala-Val, T Andl, GF Le Bras, CD Andl Activin A-mediated epithelial de-differentiation contributes to injury repair in an in vitro gastrointestinal reflux model Cytokine, 2019-07-29;123(0):154782. 2019-07-29 [PMID: 31369967] (Human)
• S Kress, J Baur, C Otto, N Burkard, J Braspennin, H Walles, J Nickel, M Metzger Evaluation of a Miniaturized Biologically Vascularized Scaffold in vitro and in vivo Sci Rep, 2018-03-16;8(1):4719. 2018-03-16 [PMID: 29549334]
• P De Berdt, P Bottemanne, J Bianco, M Alhouayek, A Diogenes, A Llyod, J Gerardo-Na, GA Brook, V Miron, GG Muccioli, AD Rieux Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion Cell. Mol. Life Sci., 2018-02-07;0(0):. 2018-02-07 [PMID: 29417177] (Human/Rat, Rat)
• Stelios Loukides Activin A and follistatin in patients with asthma. Does severity make the difference? Respirology, 2016-11-02;0(0):. 2016-11-02 [PMID: 27807906] (Human)
• Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S Activin A as a mediator of NK-dendritic cell functional interactions. J Immunol, 2014-01-06;192(3):1241-8. 2014-01-06 [PMID: 24395917] (Human)
• Weigert J, Neumeier M, Wanninger J, Schober F, Sporrer D, Weber M, Schramm A, Wurm S, Stogbauer F, Filarsky M, Schaffler A, Aslanidis C, Scholmerich J, Buechler C Adiponectin upregulates monocytic activin A but systemic levels are not altered in obesity or type 2 diabetes. Cytokine, 2009-01-06;45(2):86-91. 2009-01-06 [PMID: 19128983] (Human)
• Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide. J. Immunol., 2008-03-01;180(5):3520-34. 2008-03-01 [PMID: 18292579] (Human)
• Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB. Arthritis Rheum., 2007-11-01;56(11):3715-25. 2007-11-01 [PMID: 17968943] (Porcine)
• Eijken M, Swagemakers S, Koedam M, Steenbergen C, Derkx P, Uitterlinden AG, van der Spek PJ, Visser JA, de Jong FH, Pols HA, van Leeuwen JP The activin A-follistatin system: potent regulator of human extracellular matrix mineralization. FASEB J., 2007-04-20;21(11):2949-60. 2007-04-20 [PMID: 17449718] (Human)

FAQs for Activin A (DY338). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: INHBA