HLA DQA2 Antibody - BSA Free

Western Blot: HLA DQA2 Antibody [NBP3-12911] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with HLA DQA2 antibody (NBP3-12911) diluted at 1:500.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HLA DQA2 Antibody - BSA Free Summary

• Description: Centrifuge briefly prior to opening.
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HLA DQA2. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HLA-DQA2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for HLA DQA2 Antibody - BSA Free

• DX alpha chain
• DX-ALPHA
• HLA class II histocompatibility antigen, DQ alpha 2 chain
• HLA class II histocompatibility antigen, DQ(6) alpha chain
• HLA-DQA1
• HLA-DXAMHC class II DQA2
• major histocompatibility complex, class II, DQ alpha 2

Background

The HLA-DQA2 gene encodes a 255 amino acid long, 28 kDA HLA class II histocompatibility antigen, DQ alpha 2 chain that functions in the peptide loading of MHC class II molecules. It does so by releasing the CLIP molecule from the peptide binding site. The HLA-DQA2 gene participates in cell adhesion molecules (CAMs), antigen processing and presentation, transport of MHC II:Ii complex along Golgi to TGN, the CDC42 pathway, and in G-protein signaling in N-RAS regulation pathways. It is known to interact with genes CD4 and HLA-DQB1. HLA-DQA2 is linked to osteoarthritis, celiac disease, diabetes, asthma, thyroiditis, childhood type dermatomyositis, graft vs. host disease, narcolepsy, and lupus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HLA-DQA2