Fc epsilon RI Antibody (AER-37)

Images

 
Immunohistochemistry-Paraffin: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Staining of human mast cell in human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Flow Cytometry: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Analysis using the FITC conjugate of NBP1-43278. Staining of normal human peripheral blood cells with Anti-Human IgE PE and Mouse IgG2b K Isotype Control ...read more
Flow Cytometry: Fc epsilon RI Antibody (AER-37) [NBP1-43278] - Staining of normal human peripheral blood cells with Mouse IgG2b kappa Isotype Control Purified (green histogram) or Anti-Human Fc epsilon Receptor I a ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-P
Clone
AER-37
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Fc epsilon RI Antibody (AER-37) Summary

Immunogen
The immunogen for this antibody was FceRI alpha.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FCER1A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry-Paraffin
Application Notes
The AER-37 antibody has been tested by flow cytometric analysis of peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Reactivity Notes

This antibody is reactive to Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for Fc epsilon RI Antibody (AER-37)

  • alpha polypeptide
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
  • Fc-epsilon RI-alpha
  • FcERI
  • high affinity immunoglobulin epsilon receptor alpha-subunit
  • high affinity immunoglobulin epsilon receptor subunit alpha
  • high-affinity, of mast cells, alpha polypeptide

Background

The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-43278APC
Biotin Labeled NBP1-43522
DyLight 350 Labeled NBP1-43278UV
DyLight 405 Labeled NBP1-43278V
DyLight 488 Labeled NBP1-43278G
DyLight 680 Labeled NBP1-43278FR
DyLight 755 Labeled NBP1-43278IR
FITC Labeled NBP1-43940
PE Labeled NBP1-43278PE
PerCP Labeled NBP1-43278PCP

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Bioinformatics

Gene Symbol FCER1A