HIN-1/SCGB3A1 Antibody (368203)

• Reactivity: Mu
• Applications: WB
• Clone: 368203
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: LYOPH

HIN-1/SCGB3A1 Antibody (368203) Summary

• Immunogen: E. coli-derived recombinant mouse HIN‑1/SCGB3A1
  Phe22-Gly104
  Accession # Q920D7
• Specificity: Detects mouse HIN‑1/SCGB3A1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human HIN-1 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Otud4
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HIN-1/SCGB3A1 Antibody (368203)

• cytokine high in normal-1
• Cytokine HIN-1
• High in normal 1
• HIN1
• HIN-1
• HIN1Pneumo secretory protein 2
• LU105
• PNSP2
• PnSP-2
• PnSP-2Uteroglobin-related protein 2
• SCGB3A1
• secretoglobin family 3A member 1
• secretoglobin, family 3A, member 1
• UGRP2
• UGRP2MGC87867

Background

HIN-1, also known as secretoglobin 3A1 (SCGB3A1), PnSP-2, LuLeu-2, and UGRP-2 is an 8 kDa member of the secretoglobin family of molecules. It is synthesized as a 104 aa precursor that contains a 21 aa signal sequence and an 83 aa mature region. Based on other members of the family, HIN-1 is likely to exist as a disulfide-linked homodimer. The molecule is found in mammary and upper airway epithelium. No receptor for HIN-1 has been identified. Mature mouse HIN-1 shares 60% aa sequence identity with mature human HIN-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HIN-1/SCGB3A1 Antibody (MAB2954)(1)

Publication using MAB2954

• Yin W, Liontos A, Koepke J et al. An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea bioRxiv 1/1/2022 [PMID: 35112129]

Bioinformatics

• Gene Symbol: Otud4
• Uniprot:
  • Q920D7()