HFE Antibody

Western Blot: HFE Antibody [H00003077-D01P] - Analysis of HFE expression in transfected 293T cell line by HFE polyclonal antibody.Lane 1: HFE transfected lysate(40.10 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

HFE Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: HFE (NP_000401.1, 1 a.a. - 348 a.a.) full-length human protein. MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
• Specificity: Reacts with hemochromatosis.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HFE
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HFE Antibody

• dJ221C16.10.1
• hemochromatosis
• hereditary hemochromatosis protein HLA-H
• hereditary hemochromatosis protein
• HFE
• HFE1
• HH
• high Fe
• HLAH
• HLA-H
• HLA-HHFE1
• MGC103790
• MHC class I-like protein HFE
• MVCD7
• TFQTL2

Background

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HFE
• Entrez:
  • 3077(Human)
• Uniprot:
  • NP_000401.1(Human)